Disease-information

Reflux esophagitis is an esophageal mucosal injury that occurs secondary to retrograde flux of gastric contents into the esophagus. Clinically, this is referred to as gastroesophageal reflux disease (GERD).Fig: EsophagitisWhich PPI is Superior?Some of the present study demonstrated that Esomeprazole gave faster symptom relief in patients with R...
Key Points about Vitamin D Deficiency and Dependency Vitamin D deficiency is common and results from inadequate exposure to sunlight and inadequate dietary intake (usually occurring together) and/or from chronic kidney disease.   The deficiency can cause muscle aches and weakness, bone pain, and osteomalacia....
Published in JAMA: The Journal of the American Medical AssociationThis full article is available on the publisher's site-https://jamanetwork.com/journals/jama/fullarticle/2768929Expert comment By David Rakel MD, FAAFP Esther Millard Endowed Professor, University of Wisconsin School of Medicine & Public Health; Chair, Department of Family Medicin...
Published in JAMA: The Journal of the American Medical AssociationThis full article is available on the publisher's site-https://jamanetwork.com/journals/jama/fullarticle/2768929Expert comment By David Rakel MD, FAAFP Esther Millard Endowed Professor, University of Wisconsin School of Medicine & Public Health; Chair, Department of Family Medicin...
The authors of this study evaluated the association between weight loss and total knee or hip replacement for osteoarthritis among middle-aged and older adults with overweight or obesity. Compared with maintaining a stable weight, weight loss of >7.5% was associated with a reduced risk of total knee but not total hip replacement. A weight loss...
The study was conducted in Bangladesh among malnourished children and highly appreciated among world experts. Full article has been published in The New England Journal of Medicine.https://www.nejm.org/doi/full/10.1056/nejmoa2023294One Expert Comment: Written by David Rakel MD, FAAFP  Nutrition Is Mor...
The study was conducted in Bangladesh among malnourished children and highly appreciated among world experts. Full article has been published in The New England Journal of Medicine.https://www.nejm.org/doi/full/10.1056/nejmoa2023294One Expert Comment: Written by David Rakel MD, FAAFP  Nutrition Is Mor...
The study was conducted in Bangladesh among malnourished children and highly appreciated among world experts. Full article has been published in The New England Journal of Medicine.https://www.nejm.org/doi/full/10.1056/nejmoa2023294One Expert Comment: Written by David Rakel MD, FAAFP  Nutrition Is Mor...
GERD is a chronic disorder of the digestive system caused by the lower esophageal sphincter not closing properly. This can allow gastric acid, bile into esophagus, causing inflammation and, in some cases, tooth erosion.GERD occurs more commonly in individuals who are:Overweight or obese because of increased pressure on the abdomen.Pregnant...
Cefuroxime is a 2nd generation cephalosporin group of broad-spectrum β-lactam antibiotic.Clavulanic acid is a beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics. Clavulanic acid does have some degree of bacterial activity; its principal role is as a beta-lactamase inhibitor. Used in combination with t...
The following groups are at a particularly high risk of vitamin D deficiency:Infants and children aged 65 yearsIndividuals who have darker skin (e.g. people of South Asian ethnic origin).People who have no or limited sun exposure, including people who:  cover their skin for cultural reasons are confined in...
A Double Action Antacid & Alginate Liquid was more effective than an antacid in controlling postprandial esophageal acid exposure in GERD patients. This suggests that this main effectiveness related to its co-localization with and displacement/neutralization of the post-prandial acid pocket, rather than preventing reflux.Heartburn is...