Alimentary Pharmacology & Therapeutics: Functional dyspepsia is characterised by troublesome early satiety, fullness, or epigastric pain or burning. It can easily be overlooked as the symptoms overlap with gastro-oesophageal reflux disease and irritable bowel syndrome. It affects 10% of the population and is more prevalent in women....

TAKE-HOME MESSAGEAbout 80% of pregnant women suffer from gestational reflux disease. Most interventions are based on a “step-up” approach that begins with lifestyle modifications. If the symptoms persist despite lifestyle modification, a medical intervention can be considered. Antacids, alginates and sucralfate are the first-line t...

Antacids neutralize gastric acid and are, broadly used in the treatment of gastroesophageal reflux disease (GERD) in adults. They are utilized for more than 2,000 years, though evidence of the effectiveness and safety is limited in infants [1]. Antacids have an effect on the short-term relief of heartburn and the healing of esophagitis. Charac...

Dyspepsia is defined as having one or more symptoms of epigastric pain, burning, postprandial fullness, or early satiation. Bloating and nausea often coexist with dyspepsia but are nonspecific and are thus not included in its definition. Heartburn is also excluded from diagnostic symptom criteria for dyspepsia since it is thought to primarily...

Comparative study of PPI for symptom relief in patients with reflux esophagitis: Some of the present study demonstrated that esomeprazole gave faster symptom relief than pantoprazole, lansoprazole and omeprazole. Because: Esomeprazole has been shown to have a faster onset of anti-secretory...