Disease-information

Investigating suspected thyroid dysfunction or thyroid enlargement
NICE GUIDANCE:Indications for tests for thyroid dysfunctionConsider tests for thyroid dysfunction for adults, children and young people if there is a clinical suspicion of thyroid disease, but bear in mind that 1 symptom alone may not be indicative of thyroid disease.Offer tests for thyroid dysfunction to adults, children and young people with...
Single dose (400 mg) VS 7 day (200 mg) daily dose Itraconazole in the treatment of Tinea Versicolor
Tinea (pityriasis) versicolor is a superficial fungal infection and one of the most commonly found pigmentary disorders of skin caused by the yeast Malassezia. Multiple topical as well as systemic therapies are available for treatment. Systemic therapies are used for extensive disease, frequent relapse or where topical agents have failed. TAKE...
Seborrheic Dermatitis in Older Adults: Pathogenesis and Treatment Options
PubMed: Published on April 2022Seborrheic dermatitis (SD) is a common inflammatory skin disease, which is particularly prevalent in older adults, presenting with papulosquamous morphology in areas rich in sebaceous glands, particularly the scalp, face, and body folds.PathogenesisWhile a specific cause of seborrheic dermatitis remains largely un...
Effect of levothyroxine supplementation on pregnancy loss & preterm birth in women with subclinical hypothyroidism & thyroid autoimmunity
Human Reproduction Update Journal: Published on February, 2019Subclinical hypothyroidism (SCH) is defined as an elevated serum thyrotropin (TSH) level with normal serum thyroxine (T4) level and affects 3–8% of women of childbearing age. International guidelines advocate the use of population-based reference ranges of TSH during pregnancy; h...
Effect of levothyroxine supplementation on pregnancy loss & preterm birth in women with subclinical hypothyroidism & thyroid autoimmunity
Human Reproduction Update Journal: Published on February, 2019Subclinical hypothyroidism (SCH) is defined as an elevated serum thyrotropin (TSH) level with normal serum thyroxine (T4) level and affects 3–8% of women of childbearing age. International guidelines advocate the use of population-based reference ranges of TSH during pregnancy; h...
Younger Age at Menarche Increase the Risk for Chronic Pain Later in Life
Take Home Messages:Women who were younger at the time of their first menstrual period are more likely to report chronic pain in adulthood, according to a study published in PAIN journal.Researchers study to examine associations between age at menarche and chronic pain among women aged 30 to 99 years.Early menarche is associated with pain...
A Comparative Study on Efficacy of Norethisterone and Medroxyprogestrone in the Management of DUB
Social Science Research Network (SSRN) Elsevier Journal: Published on April, 2023Dysfunctional uterine bleeding (DUB) is defined as bleeding from the uterine corpus that is abnormal in regularity, volume, frequency, or duration and occurs in the absence of pregnancy. Dysfunctional Uterine Bleeding (DUB) is defined as abnormal uterine...
A Comparative Study on Efficacy of Norethisterone and Medroxyprogestrone in the Management of DUB
Social Science Research Network (SSRN) Elsevier Journal: Published on April, 2023Dysfunctional uterine bleeding (DUB) is defined as bleeding from the uterine corpus that is abnormal in regularity, volume, frequency, or duration and occurs in the absence of pregnancy. Dysfunctional Uterine Bleeding (DUB) is defined as abnormal uterine...
Efficacy and tolerability of Luliconazole cream 1% for Dermatophytoses: A Meta-analysis
The Journal of Dermatology:Luliconazole Cream, 1% is an azole antifungal indicated for the topical treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum and Epidermophyton floccosum.TAKE HOME MESSAGES: Authors evaluated the efficacy and safety of luliconazole cream 1% in the treatmen...
Tinea capitis in children: a systematic review of management
European Academy of Dermatology and Venereology: Published on July, 2018Tinea capitis is the most common cutaneous fungal infection in children.TAKE HOME MESSAGEThis review aims to evaluate the differences that exist between medications for the treatment of tinea capitis, to determine whether there are any significant adverse effects associated...
Aspirin vs Clopidogrel for Chronic Maintenance Monotherapy after PCI: Long-Term Outcomes
AHA Journals (Circulation): Published on November, 2022Once patients have completed their dual antiplatelet therapy, we need to stop one of the medications — which one — ASA or clopidogrel? For many of us, we will keep the ASA and get rid of the other agent like clopidogrel.This study in Korea included 5438 patients who had PCI with drug-elutin...
Levothyroxine Therapy in Elderly Patients with Hypothyroidism
Frontiers in Endocrinology: Published on March 2021Hypothyroidism is a common condition caused by thyroid hormone deficiency. The prevalence of hypothyroidism increases with age and subclinical hypothyroidism affects up to 15% of adults 65 years of age or older.Levothyroxine (L-T4) treatment of overt hypothyroidism can be more challenging...