Disease-information
The New England Journal of Medicine:
Postpartum
hemorrhage is a major cause of maternal death and severe maternal complications
after childbirth. Currently, the prophylactic administration of a uterotonic
agent immediately after delivery is recommended for all women as the only
procedure that has been proved to reduce rates of postpartum...
European Heart Journal:
Management of
cardiometabolic risk factors should become a priority for physicians. The
long-term impact of COVID-19 on cardiovascular (CV) health and mortality is
also emerging as a major global concern.
Non-pharmacological
supportive approaches:
The management of long COVID tends to be
largely supportive....
Take Home Message:
Tinea infections are caused by
dermatophytes. The term tinea means fungal infection, whereas dermatophyte
refers to the fungal organisms that cause tinea. Dermatophytes include three
genera: Trichophyton, Microsporum, and Epidermophyton.
Dermatophytes can be classified
into three groups: Trichophyton (which causes...
Nonpharmacologic measures
Patients should be encouraged to
wear loose-fitting garments made of cotton or synthetic materials designed to
wick moisture away from the surface. Socks should have similar properties.
Areas likely to become infected
should be dried completely before being covered with clothes. Patients should
also be advis...
JAMA Neurology:
Early and prodromal features of
Parkinson disease (PD) have increasing relevance as the quest for potential
disease-modifying therapies is expanding.
KEY TAKE-HOME MESSAGE
Question What
are the prediagnostic manifestations of Parkinson disease (PD) presented in the
primary care setting?
Findings This
case-contr...
Journal of Drugs in Dermatology:
Onychomycosis—a
fungal infection of the nail bed or plate caused by dermatophytes,
non-dermatophyte molds, or yeasts.
Treatment
of onychomycosis is multifactorial and relies predominantly on the severity of
nail disease and patient comorbidities.
Diagnosis:
For diagnosis of onychomycosis,
lo...
Pityriasis versicolor, also known
as tinea versicolor, is a common, benign, superficial fungal infection of the
skin. Tinea versicolor is not considered contagious.
Pityriasis versicolor is caused by
Malassezia fungus, also known as Pityrosporum. It is a component of normal skin
flora. It is more common in warm and humid conditions.
C...
Pediatric Dermatology:
TAKE-HOME MESSAGE
The authors performed a network
meta-analysis of monotherapies used to treat tinea capitis. Griseofulvin,
terbinafine, ketoconazole, itraconazole, and fluconazole were compared.
This network meta-analysis compares
the efficacy of five different systemic monotherapies for tinea capitis.
Alth...
Trauma is the leading cause of
death and disability worldwide. In both military and civilian settings, hemorrhage
remains the most common cause of preventable death after traumatic injury. In
recent years, there has been considerable interest in antifibrinolytic agents
for the prevention of hemorrhagic death in severe trauma patients.
T...
Annals of Internal Medicine:
TAKE-HOME MESSAGE
In this UK Biobank study, the
authors sought to evaluate the correlation between serum testosterone levels
and cardiac events, finding no association between total testosterone and risk
for major adverse cardiovascular events (MACE).
Men with lower total testosterone
concentrations wer...
Take Home Messages:
Authors propose a new conceptual
model for PD pathogenesis, in which disease-associated factors are divided into
three categories: triggers, facilitators, and aggravators.
Triggers are agents or events that begin the disease process; these
factors are necessary but insufficient for PD to develop.
Facilitators ar...
The American College of Cardiology (ACC) & The New England Journal of
Medicine (NEJM):
Key Prescribing Notes:
Perioperative bleeding is common
complications in patients undergoing noncardiac surgery, is associated with
increased morbidity and mortality.
The goal of the POISE-3 trial was
to determine whether tranexamic acid, when u...
