Disease-information
Nonpharmacologic measures
Patients should be encouraged to
wear loose-fitting garments made of cotton or synthetic materials designed to
wick moisture away from the surface. Socks should have similar properties.
Areas likely to become infected
should be dried completely before being covered with clothes. Patients should
also be advis...
JAMA Neurology:
Early and prodromal features of
Parkinson disease (PD) have increasing relevance as the quest for potential
disease-modifying therapies is expanding.
KEY TAKE-HOME MESSAGE
Question What
are the prediagnostic manifestations of Parkinson disease (PD) presented in the
primary care setting?
Findings This
case-contr...
Journal of Drugs in Dermatology:
Onychomycosis—a
fungal infection of the nail bed or plate caused by dermatophytes,
non-dermatophyte molds, or yeasts.
Treatment
of onychomycosis is multifactorial and relies predominantly on the severity of
nail disease and patient comorbidities.
Diagnosis:
For diagnosis of onychomycosis,
lo...
Pityriasis versicolor, also known
as tinea versicolor, is a common, benign, superficial fungal infection of the
skin. Tinea versicolor is not considered contagious.
Pityriasis versicolor is caused by
Malassezia fungus, also known as Pityrosporum. It is a component of normal skin
flora. It is more common in warm and humid conditions.
C...
Pediatric Dermatology:
TAKE-HOME MESSAGE
The authors performed a network
meta-analysis of monotherapies used to treat tinea capitis. Griseofulvin,
terbinafine, ketoconazole, itraconazole, and fluconazole were compared.
This network meta-analysis compares
the efficacy of five different systemic monotherapies for tinea capitis.
Alth...
Trauma is the leading cause of
death and disability worldwide. In both military and civilian settings, hemorrhage
remains the most common cause of preventable death after traumatic injury. In
recent years, there has been considerable interest in antifibrinolytic agents
for the prevention of hemorrhagic death in severe trauma patients.
T...
Annals of Internal Medicine:
TAKE-HOME MESSAGE
In this UK Biobank study, the
authors sought to evaluate the correlation between serum testosterone levels
and cardiac events, finding no association between total testosterone and risk
for major adverse cardiovascular events (MACE).
Men with lower total testosterone
concentrations wer...
Take Home Messages:
Authors propose a new conceptual
model for PD pathogenesis, in which disease-associated factors are divided into
three categories: triggers, facilitators, and aggravators.
Triggers are agents or events that begin the disease process; these
factors are necessary but insufficient for PD to develop.
Facilitators ar...
The American College of Cardiology (ACC) & The New England Journal of
Medicine (NEJM):
Key Prescribing Notes:
Perioperative bleeding is common
complications in patients undergoing noncardiac surgery, is associated with
increased morbidity and mortality.
The goal of the POISE-3 trial was
to determine whether tranexamic acid, when u...
Journal of Endometriosis and Pelvic Pain Disorders:
Adenomyosis is a common
gynecological disease in premenopausal women and late reproductive age. The
most common symptoms are progressive dysmenorrhea, chronic pelvic pain,
dyspareunia, heavy menstrual bleeding, and abnormal uterine bleeding.
The severity and frequency of symptoms...
Overview of OsteoporosisOsteoporosis is a disease
characterized by low bone mass and deterioration of bone tissue and bone
structure, which can lead to increased bone fragility and risk of fracture. The most common fractures associated
with osteoporosis are in the hip, spine, wrist, and shoulder.
Osteoporosis is the major cause
o...
Nature Medicine
Post-acute
sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—can
involve the pulmonary and several extrapulmonary organs, including the
cardiovascular system. A few studies have investigated cardiovascular outcomes
in the post-acute phase of the COVID-19; however, most were limited to
hospitalized...
