Coronavirus-clinical-updates

The World Health Organization (WHO) classified the sub-variant of the Omicron strain JN.1 as a "variant of interest",because of "its rapidly increasing spread".JN.1 has been found in many countries around the world, including India, China, UK and the United States.TAKE HOME MESSAGEIt is descended from the BA.2.86 (Pirola) variant.It appears able...
Clinical Neurophysiology: April 2023Long term symptoms following COVID-19 (Long COVID) now affects a large number of patients with estimates of up to 100 million people world-wide.Prolonged “long-COVID” (P-L–COVID), seen several months after even a mild COVID-19 infection, is characterized by a complexity of neuromuscular, musculoskeletal, and...
Omicron subvariant XBB.1.16, the strain was first identified in January and has been monitored by the World Health Organisation (WHO) since 22 March, which upgraded it to a “variant of interest” in mid-April.Cases of Omicron variant XBB are mounting in China, forming a new wave expected to crest around 65 million cases...
JAMA: The Journal of the American Medical Association: Published on November, 2022Despite advances in treatment of COVID-19, additional therapies are needed, particularly in the outpatient setting. Novel oral antivirals have been authorized for high-risk individuals. Numerous repurposed drugs have been investigated for COVID-19.Ivermectin, an a...
Nature Medicine and The British Medical Journal (BMJ): Published July, 2022Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID.People experiencing long covid have reported a wider set of symptoms tha...
JAMA Network: November, 2022After the worldwide outbreak leading to millions of acute cases and thousands of deaths, another important development is the occurrence or persistence of symptoms after the acute phase of SARS-CoV-2 infection (ie, long COVID or post–COVID-19).More than 100 post–COVID-19 symptoms affecting multiple systems (eg, cardi...
The persistence, severity, and disability associated with post-COVID conditions, often referred to as "long COVID," pose significant diagnostic and management challenges. Some patients who have been infected with SARS-CoV-2, the virus that causes COVID-19, have new, recurring, or ongoing symptoms and clinical findings four or more weeks after infec...
Neurology (American Academy of Neurology) Journal: Published on March, 2022Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause long-term disability (long COVID) with new neurologic manifestations after even mild infections. Reports of peripheral neuropathy include Guillain-Barré syndrome, mononeuritis multiplex, brachial ple...
A new and highly transmissible BF.7 strain of the Omicron variant has been found to be behind a wider surge of COVID infections in China and is spreading rapidly around the world. It has been found in the United States, Denmark, Germany, France, and India. The highly contagious new Omicron sub-variant of coronavirus, BF.7, has been detected in...
NICE guidelines:Take Home MessagesDo not offer an antibiotic for preventing or treating Pneumonia if SARS-CoV-2, another virus, or a fungal infection is likely to be the cause.Evidence as of March 2021 suggests that bacterial co-infection occurs in less than about 8% of people with COVID-19, and could be as low as 0.1% in people in hospital wit...
NICE guidelines:Antibiotic treatment in the communityRecommendationsDo not offer an antibiotic for preventing secondary bacterial pneumonia in people with COVID 19. If a person has suspected or confirmed secondary bacterial pneumonia, start antibiotic treatment as soon as possible. Advise people to seek medical help without delay if their sympt...
Journal of Neuro-Ophthalmology: TAKE-HOME MESSAGE This study reviewed published literature regarding the ophthalmic manifestations of COVID-19. Findings revealed that eye pain was caused by conjunctivitis, episcleritis, scleritis, and optic neuritis, and headache was the result of trigeminal nerve invasion and vascular effects. These mani...