Disease-information

The New England Journal of Medicine: Postpartum hemorrhage remains a leading cause of severe maternal complications and death worldwide. Prophylactic administration of an uterotonic agent is recommended to reduce the risk of postpartum hemorrhage. Tranexamic acid has emerged in the past decade as another candidate drug to prevent blood l...
A meta-analysis of the randomized controlled trials: The American Journal of Emergency Medicine Trauma remains a leading cause of death worldwide, and the management of injured patients at risk for hemorrhage has evolved over time. Interventions provided to injured patients during prehospital care, close to the time of injury, result...
NICE guideline: Suspect Parkinson's disease in people presenting with tremor, stiffness, slowness, balance problems and/or gait disorders. If Parkinson's disease is suspected, refer people quickly and untreated to a specialist with expertise in the differential diagnosis of this condition. Clinical diagnosis Diagnose Parkinso...
Introduction Parkinson’s disease (PD) is a neurodegenerative disease resulting from progressive death of the dopaminergic neurons in the brainstem, particularly the substantia nigra pars compacta (SNc). Besides the hallmark motor symptoms (hypokinesia, rest tremor, rigidity, and postural instability), PD patients have non-motor symptoms...
Progesterone maintains pregnancy by enhancing uterine quiescence. During early pregnancy, the syncytiotrophoblast secretes human chorionic gonadotropin (hCG), which stimulates progesterone production in the corpus luteum by preventing regression of this tissue. Low serum hCG or progesterone levels may predict first trimester abortions....
Treatment guidelines for type 2 diabetes mellitus (T2DM) recommend initiating pharmacotherapy with an oral antidiabetic drug (OAD) to reduce hyperglycaemia when diet and exercise are inadequate. International guidelines recommend metformin as the first OAD, whereas Japanese guidelines recognize that other OADs may be more appropriate i...
Metabolic Syndrome and Related Disorders Journal: Published Online: 15 Feb 2022 Seborrheic dermatitis (SD) is a common, chronic inflammatory disease with relapses and remissions. TAKE HOME MESSAGE: This study aimed to evaluate metabolic syndrome (MS) and glucose metabolism disorders in patients with SD. The study results showed...
The management of gastroesophageal reflux disease (GERD) has been revolutionized with the development of proton pump inhibitors (PPIs). Unfortunately, due to the inherent pharmacokinetic and pharmacodynamic profiles of conventional PPIs, many patients continue to suffer from symptoms related to GERD despite appropriate use of PPIs. Curr...
JAMA: The Journal of the American Medical Association: Published on April 5, 2022 Epilepsy affects approximately 65 million people worldwide. Persistent seizures are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) over 12-month follow-up. The primary goal of epilepsy treatment is to eliminate seiz...
American Diabetes Association (ADA) Professional Practice Committee: Recommendations Treatment Strategies Lifestyle Intervention: Recommendation For patients with blood pressure >120/80 mmHg, lifestyle intervention consists of weight loss when indicated, a Dietary Approaches to Stop Hypertension (DASH)-style eating pattern inclu...
American Diabetes Association (ADA) Professional Practice Committee: Recommendations Treatment Strategies Lifestyle Intervention: Recommendation For patients with blood pressure >120/80 mmHg, lifestyle intervention consists of weight loss when indicated, a Dietary Approaches to Stop Hypertension (DASH)-style eating pattern inclu...
International Journal of Basic & Clinical Pharmacology: Published on July 2021 Superficial Tinea corporis is said to be recurrent when there is recurrence of the disease within 6 weeks after the completion of treatment. The prevalence of superficial mycosis is on the rise with change in spectrum of infection and isolation of some uncommo...