Disease-information
Studies clarify menopausal HT’s impact on breast cancer riskOne of the greatest concerns of women who are considering
Menopausal Hormone Therapy (MHT) is the relationship between hormone use and
breast cancer. Data from the The Women’s Health Initiative (WHI) suggest an
increase in risk with combined estrogen-progestin therapy, but a reduction i...
JAMA Internal MedicineTAKE-HOME MESSAGEThis retrospective study evaluated
the association between statin initiation and diabetes progression. Progression
of diabetes occurred in significantly more statin users. There was a
dose–response relationship with higher-intensity statin use.The study examined 12 years of data
on patients covered by the...
JAMA Internal MedicineTAKE-HOME MESSAGEThis retrospective study evaluated
the association between statin initiation and diabetes progression. Progression
of diabetes occurred in significantly more statin users. There was a
dose–response relationship with higher-intensity statin use.The study examined 12 years of data
on patients covered by the...
JAMA NeurologyTAKE-HOME MESSAGE
Evidence is rapidly accumulating of
the benefit of exercise and physical activity in Parkinson disease (PD). The
authors conducted a nationwide population-based cohort study of 10,699
individuals with PD, evaluating the association of physical activity (obtained
from self-reported structured questionnaires...
Generalized anxiety disorder (GAD)
is the most common mental disorders. The hallmark of GAD is excessive,
out-of-control worry. This condition can negatively impact a patient's quality of
life and disrupt important activities of daily living. Women are twice as
likely as men to have the disorder. It often begins in childhood or adolescence...
Generalized anxiety disorder (GAD)
is the most common mental disorders. The hallmark of GAD is excessive,
out-of-control worry. This condition can negatively impact a patient's quality of
life and disrupt important activities of daily living. Women are twice as
likely as men to have the disorder. It often begins in childhood or adolescence...
Journal of the American Medical
Association (JAMA)
SurgeryTranexamic
acid is an antifibrinolytic compound which inhibits fibrinolysis by blocking
the binding of plasminogen and plasmin to fibrin, thus preventing dissolution
of the haemostatic plug.
TAKE-HOME MESSAGE
Question Is
intravenous administration of tranexamic acid associated wi...
Motor symptoms are those that
affect movement of the body. These are the cardinal symptoms of PD. The main
motor symptoms of PD are tremor, slowness of movement (bradykinesia), stiffness
(rigidity), and poor balance (postural instability). These symptoms are usually
mild in the early stages of the disease. PD patients show additional mo...
The New England Journal of Medicine:
Postpartum
hemorrhage remains a leading cause of severe maternal complications and death worldwide.
Prophylactic administration of an uterotonic agent is recommended to reduce the
risk of postpartum hemorrhage. Tranexamic acid has emerged in the past decade
as another candidate drug to prevent blood l...
A meta-analysis of the randomized
controlled trials: The American
Journal of Emergency Medicine
Trauma remains a leading cause of
death worldwide, and the management of injured patients at risk for hemorrhage
has evolved over time.
Interventions provided to injured
patients during prehospital care, close to the time of injury, result...
NICE guideline:
Suspect
Parkinson's disease in people presenting with tremor, stiffness, slowness,
balance problems and/or gait disorders.
If
Parkinson's disease is suspected, refer people quickly and untreated to a
specialist with expertise in the differential diagnosis of this condition.
Clinical diagnosis
Diagnose
Parkinso...
Introduction
Parkinson’s disease (PD) is a
neurodegenerative disease resulting from progressive death of the dopaminergic
neurons in the brainstem, particularly the substantia nigra pars compacta
(SNc). Besides the hallmark motor symptoms (hypokinesia, rest tremor, rigidity,
and postural instability), PD patients have non-motor symptoms...
