Disease-information
The British Journal of Dermatology: Published: 16
September 2024Retinoids, widely used in
dermatology for treating acne and various skin conditions, have raised concerns
regarding potential side effects, particularly sexual dysfunction. Although
retinoids are effective in managing skin conditions, their association with sexual
dysfunction is b...
Stepwise Approach of
Dengue Case ManagementPatients Group A: These are patients who are dengue
patients without warning sign and they may be sent home. These patients are
able to tolerate adequate volumes of oral fluids, pass urine at least once
every six hours. Patients Group B: These include patients with warning
signs. These are patients wh...
Monkeypox cases have been reported
in several countries in Africa such as Congo and Pakistan recently. The World Health Organization
(WHO) announced on 14 August 2024 that it declared MPox a ‘public health
emergency of international concern.
Monkeypox is a viral zoonosis (a
virus transmitted to humans from animals) with symptoms very...
Journal of the American Academy of Dermatology: July 2024Male androgenetic alopecia (AGA), or male pattern hair loss,
is characterized by gradual thinning of hair on the vertex of the scalp and
recession of the frontal hairline. FDA-approved therapies are restricted to topical minoxidil
and oral finasteride. Effective non–FDA-approved...
The American Society of Colon and Rectal SurgeonsDiseases of the Colon and Rectum: Published October, 2024IntroductionChronic constipation is a prevalent condition that
significantly impacts patients' quality of life. The American Society of Colon
and Rectal Surgeons (ASCRS) has developed clinical practice guidelines to
provide evidence-based re...
BMJ: British Medical Journal: Published September 2024Migraine is a neurological disorder characterized by
disabling, recurrent episodes of moderate to severe headache and accompanying
symptoms lasting up to 72 hours. The acute management of migraine episodes consists of drug
interventions aimed at providing rapid and sustained pain relief, and,...
Archives of Dermatological Research: Published: August 2024Vitiligo, an autoimmune condition characterized by
depigmented skin patches due to the loss of functional melanocytes, has been
linked to dysregulation in the JAK-STAT signaling pathway, particularly in
IFN-g signaling. The use of JAK inhibitors, such as ruxolitinib cream, a JAK1
and JA...
Journal of the American College of Cardiology: August,
2024Single-pill combinations of 3 or
more low-dose blood pressure (BP)-lowering drugs hold promise for initial or
early treatment of hypertension.The
Authors conducted a placebo-controlled trial of a new single-pill
combination containing low doses of telmisartan, amlodipine, and indapamid...
The Lancet
Diabetes & Endocrinology: Published: March, 2024Atherosclerotic cardiovascular
disease is a leading cause of death worldwide, and LDL cholesterol is a major
causal risk factor.Diabetes substantially increases
the risk of atherosclerotic cardiovascular disease.TAKE-HOME MESSAGEIn this
participant-level meta-analysis of 19 trials, sta...
Pharmacologic Approaches to
Glycemic Treatment:
The goals
in caring for patients with diabetes mellitus are to eliminate symptoms and to
prevent, or at least slow, the development of complications. FIND BELOW TREATMENT RECOMMENDATIONS FOR TYPE 2 DIABETES:
Management of hypertensionMany guidelines exist for the management of hypertension.
Most groups, including the JNC, the American Diabetes Associate (ADA), and the
American Heart Association/American Stroke Association (AHA/ASA) recommend
lifestyle modification as the first step in managing hypertension.Lifestyle modificationsJNC 7 recommendation...
