Disease-information

Comparative efficacy of Dexlansoprazole vs. esomeprazole in the treatment of Gastro-Esophageal Reflux Disease
Dexlansoprazole is a new proton pump inhibitor (PPI) with a dual delayed-release system. Both dexlansoprazole and esomeprazole are an enantiomer of lansoprazole and omeprazole respectively.TAKE HOME MESSAGEThis study aims to compare the efficacy of Dexlansoprazole with Esomeprazole in healing erosive oesophagitis (EO), the maintenance of healed...
The Effect of Dexlansoprazole on Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis
International Journal of Molecular Science: Published on January 2024Gastroesophageal reflux disease (GERD) is a common disease of the digestive system with a worldwide prevalence of 8 to 33% and is characterized by the persistent reflux of gastroduodenal content that ascends through the esophageal tube, causing esophageal and extraesophageal...
Effectiveness of SGLT2 Inhibitors vs DPP-4 Inhibitors on Liver Function in Patients with Type 2 Diabetes
Diabetes, Obesity & Metabolism Journal: Published: December 2023Type 2 diabetes (T2D) and liver diseases are closely associated. T2D is an independent risk factor for chronic liver diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD), non-alcoholic steatohepatitis, cirrhosis and hepatocellular carcinoma...
Overview of the Diagnosis and Management of Seborrheic Dermatitis
Clinical, Cosmetic and Investigational Dermatology: Published on December 2022Seborrheic dermatitis (SD) is a common chronic inflammatory skin disorder that most commonly affects young adults, and less often children. In adolescents and adults, SD clinical presentation may range from a mild scalp scaling to diffuse white, yellowish patches in...
Why does Pityriasis versicolor often recurs? Clinical features & Treatment with Pictorial details
Importance: Pityriasis versicolor generally clears satisfactorily with treatment but often recurs when conditions are suitable for malassezia to proliferate. It recurs when the weather becomes warm and humid again. Regular use of topical treatment minimizes this risk. The color may persist for weeks or months, particularly the hypopi...
Topical ketoconazole: a systematic review of current dermatological applications and future developments
Ketoconazole is in a class of antifungal medications called imidazoles. It works by inhibiting the growth of fungi that cause the infection. Topical ketoconazole is indicated for the treatment of cutaneous candidosis (including vulvitis), tinea (pityriasis) versicolor and seborrhoeic dermatitis caused by Malassezia (previously called Pi...
Evaluating Primary Treatment Outcomes in Individuals Presenting With Advanced Glaucoma
Ophthalmology: The American Academy of Ophthalmology: Published: January, 2024Sight loss from glaucoma is often preventable with early diagnosis and treatment. Reducing IOP is the only proven effective treatment for glaucoma. Better IOP control at an early stage reduces the risk of further progression. Primary treatment options for advanced gl...
Best Practices for the Treatment of Melasma, With a Focus on Patients with Skin of Color
Journal of the American Academy of Dermatology: Published: September, 2023Melasma is a chronic pigmentary disorder with a complex and multifactorial etiology. In this manuscript, the authors present a set of consensus-based recommendations and provide a comprehensive overview of how to manage melasma in daily clinical practice. TAKE-HOME MESS...
Recent advances in therapies for Onychomycosis and its management
PubMed Central: Published June, 2019Onychomycosis is a fungal infection occurring in the nails and may affect the adjacent skin. Typically, it manifests as discoloration of the nail, nail plate thickening, and onycholysis. It is the most common nail pathology and accounts for about 90% of toenail infections worldwide.At present, there are sever...
Association of Daily Low-Dose Aspirin with Incident Type 2 Diabetes in Community-Dwelling Healthy Older Adults
The Lancet Diabetes & Endocrinology: Published December, 2023Inflammation has been implicated in the pathogenesis of diabetes. This study investigated the randomised treatment effect of low-dose aspirin on incident type 2 diabetes and fasting plasma glucose (FPG) concentrations among older adults.TAKE-HOME MESSAGEThis post hoc analysis of...
Is Super Bioavailable Itraconazole better than Conventional Itraconazole?
Due to the changing face of dermatophytosis in India, many dermatologists practice different dosing patterns of itraconazole (ITZ). Recently, a new form of ITZ, super-bioavailable ITZ (SBITZ), has been commercialized to overcome the pharmacokinetic challenges of conventional ITZ (CITZ). ITZ is a weak base lipophilic molecule with a limite...
Nipah virus Outbreak: Bangladesh reports highest deaths in 7 years: IEDCR
More about Nipah virus infection: This year in Bangladesh, the Nipah virus has claimed the lives of ten individuals, marking the highest death toll from the infection in seven years. With 71% death rate, Nipah is deadliest infectious disease in Bangladesh.HIGHLIGHTSNipah virus has claimed the lives of ten individuals this year An additional 14 p...