Dermatologic-disorders

Association between Treatment with Retinoids and Sexual Dysfunction
The British Journal of Dermatology: Published: 16 September 2024Retinoids, widely used in dermatology for treating acne and various skin conditions, have raised concerns regarding potential side effects, particularly sexual dysfunction. Although retinoids are effective in managing skin conditions, their association with sexual dysfunction is b...
Outcomes of Treatment with Botulinum Toxin in Males with Androgenetic Alopecia
Journal of the American Academy of Dermatology: July 2024Male androgenetic alopecia (AGA), or male pattern hair loss, is characterized by gradual thinning of hair on the vertex of the scalp and recession of the frontal hairline. FDA-approved therapies are restricted to topical minoxidil and oral finasteride. Effective non–FDA-approved...
Efficacy of Treatment with Topical Ruxolitinib Cream in Patients with Vitiligo
Archives of Dermatological Research: Published: August 2024Vitiligo, an autoimmune condition characterized by depigmented skin patches due to the loss of functional melanocytes, has been linked to dysregulation in the JAK-STAT signaling pathway, particularly in IFN-g signaling. The use of JAK inhibitors, such as ruxolitinib cream, a JAK1 and JA...
Overview of the Diagnosis and Management of Seborrheic Dermatitis
Clinical, Cosmetic and Investigational Dermatology: Published on December 2022Seborrheic dermatitis (SD) is a common chronic inflammatory skin disorder that most commonly affects young adults, and less often children. In adolescents and adults, SD clinical presentation may range from a mild scalp scaling to diffuse white, yellowish patches in...
Why does Pityriasis versicolor often recurs? Clinical features & Treatment with Pictorial details
Importance: Pityriasis versicolor generally clears satisfactorily with treatment but often recurs when conditions are suitable for malassezia to proliferate. It recurs when the weather becomes warm and humid again. Regular use of topical treatment minimizes this risk. The color may persist for weeks or months, particularly the hypopi...
Topical ketoconazole: a systematic review of current dermatological applications and future developments
Ketoconazole is in a class of antifungal medications called imidazoles. It works by inhibiting the growth of fungi that cause the infection. Topical ketoconazole is indicated for the treatment of cutaneous candidosis (including vulvitis), tinea (pityriasis) versicolor and seborrhoeic dermatitis caused by Malassezia (previously called Pi...
Best Practices for the Treatment of Melasma, With a Focus on Patients with Skin of Color
Journal of the American Academy of Dermatology: Published: September, 2023Melasma is a chronic pigmentary disorder with a complex and multifactorial etiology. In this manuscript, the authors present a set of consensus-based recommendations and provide a comprehensive overview of how to manage melasma in daily clinical practice. TAKE-HOME MESS...
Recent advances in therapies for Onychomycosis and its management
PubMed Central: Published June, 2019Onychomycosis is a fungal infection occurring in the nails and may affect the adjacent skin. Typically, it manifests as discoloration of the nail, nail plate thickening, and onycholysis. It is the most common nail pathology and accounts for about 90% of toenail infections worldwide.At present, there are sever...
Is Super Bioavailable Itraconazole better than Conventional Itraconazole?
Due to the changing face of dermatophytosis in India, many dermatologists practice different dosing patterns of itraconazole (ITZ). Recently, a new form of ITZ, super-bioavailable ITZ (SBITZ), has been commercialized to overcome the pharmacokinetic challenges of conventional ITZ (CITZ). ITZ is a weak base lipophilic molecule with a limite...
Combination of Terbinafine twice daily and Itraconazole twice in a pulse dose in resistant Tinea infection
International Journal of Research in Dermatology: March, 2022Tinea caused by trichophyton,    microsporum,    and epidermophyton is the most common fungal infection affecting   20–25%   population globally,   with varying geographic distribution.Due to  Bangladesh’s hot and humid cli...
Effectiveness of Luliconazole for the Treatment of Tinea Infections
The prevalence of superficial fungal infections across the globe is increasing from 20-25%. Superficial infections are mostly caused by dermatophytes. Depending on the site affected, the dermatophytes are clinically classified as Tinea capitis (head), Tinea faciei (face), Tinea barbae (beard), Tinea manus (hand), Tinea corporis (body), Tinea c...
Oral Medications to Treat Toenail Fungal Infection
JAMA: The Journal of the American Medical AssociationThe authors investigated different oral antifungal medications used to treat toenail fungal infections.TAKE-HOME MESSAGECompared with placebo, high-quality evidence supports better clinical (ie, normal appearance of the toenail) and mycological (negative culture, microscopy, or both) results...