Dermatologic-disorders

Cracked heels, or heel fissures, are caused by dry, thickened skin around the heels, often resulting in discomfort, pain, and potential complications like infections or cellulitis.Common in elderly individuals, diabetics, and those with prolonged weight-bearing activities, contributing factors include dry skin, improper footwear, medical condit...
Xeroderma, also known as Dry skin, xerosis cutis, or asteatosis, is a prevalent condition resulting from inadequate hydrolipids in the skin.It manifests as roughness, tightness, scaling, and flaking, often leading to pruritus, excoriations, and an increased risk of infections. The condition may lead to pruritus, resulting in excoriations and an...
The British Journal of Dermatology: Published: 16 September 2024Retinoids, widely used in dermatology for treating acne and various skin conditions, have raised concerns regarding potential side effects, particularly sexual dysfunction. Although retinoids are effective in managing skin conditions, their association with sexual dysfunction is b...
Journal of the American Academy of Dermatology: July 2024Male androgenetic alopecia (AGA), or male pattern hair loss, is characterized by gradual thinning of hair on the vertex of the scalp and recession of the frontal hairline. FDA-approved therapies are restricted to topical minoxidil and oral finasteride. Effective non–FDA-approved...
Archives of Dermatological Research: Published: August 2024Vitiligo, an autoimmune condition characterized by depigmented skin patches due to the loss of functional melanocytes, has been linked to dysregulation in the JAK-STAT signaling pathway, particularly in IFN-g signaling. The use of JAK inhibitors, such as ruxolitinib cream, a JAK1 and JA...
Clinical, Cosmetic and Investigational Dermatology: Published on December 2022Seborrheic dermatitis (SD) is a common chronic inflammatory skin disorder that most commonly affects young adults, and less often children. In adolescents and adults, SD clinical presentation may range from a mild scalp scaling to diffuse white, yellowish patches in...
Importance: Pityriasis versicolor generally clears satisfactorily with treatment but often recurs when conditions are suitable for malassezia to proliferate. It recurs when the weather becomes warm and humid again. Regular use of topical treatment minimizes this risk. The color may persist for weeks or months, particularly the hypopi...
Ketoconazole is in a class of antifungal medications called imidazoles. It works by inhibiting the growth of fungi that cause the infection. Topical ketoconazole is indicated for the treatment of cutaneous candidosis (including vulvitis), tinea (pityriasis) versicolor and seborrhoeic dermatitis caused by Malassezia (previously called Pi...
Journal of the American Academy of Dermatology: Published: September, 2023Melasma is a chronic pigmentary disorder with a complex and multifactorial etiology. In this manuscript, the authors present a set of consensus-based recommendations and provide a comprehensive overview of how to manage melasma in daily clinical practice. TAKE-HOME MESS...
PubMed Central: Published June, 2019Onychomycosis is a fungal infection occurring in the nails and may affect the adjacent skin. Typically, it manifests as discoloration of the nail, nail plate thickening, and onycholysis. It is the most common nail pathology and accounts for about 90% of toenail infections worldwide.At present, there are sever...
Due to the changing face of dermatophytosis in India, many dermatologists practice different dosing patterns of itraconazole (ITZ). Recently, a new form of ITZ, super-bioavailable ITZ (SBITZ), has been commercialized to overcome the pharmacokinetic challenges of conventional ITZ (CITZ). ITZ is a weak base lipophilic molecule with a limite...
International Journal of Research in Dermatology: March, 2022Tinea caused by trichophyton,    microsporum,    and epidermophyton is the most common fungal infection affecting   20–25%   population globally,   with varying geographic distribution.Due to  Bangladesh’s hot and humid cli...