Disease-information

Migraine as a primary headache disorder with substantial pain is included in the 20 most disabling diseases according to the World Health Organization.Lifestyle management, acute treatment, and preventive treatment are three approaches to treat migraine. Prophylactic therapy for migraine is recommended in patients with four or more attacks per...
Gastrointestinal (GI) bleeding is the most common GI diagnosis necessitating. Upper GI bleeding (UGIB) refers to bleeding originating from sites in the esophagus, stomach, or duodenum.AbstractThe American Journal of Gastroenterology society performed systematic reviews addressing predefined clinical questions to develop recommendations with the...
The role of CalciumCalcium is a key structural component of bone and is built into bone as a mineral complex that includes calcium and phosphate. Calcium is a major building-block of bone – the skeleton houses 99% of the body’s calcium stores. The calcium in bones also acts as a reservoir for maintaining calcium levels in the blood, which is n...
TAKE-HOME MESSAGE Menopausal hormone therapy has been associated with various malignancies. In this Swedish registry study, the authors investigated the use of menopausal hormone therapy and risk of colorectal cancer.    The study found that Menopausal hormone therapy was associated with overall reduced odds for co...
TAKE-HOME MESSAGE Menopausal hormone therapy has been associated with various malignancies. In this Swedish registry study, the authors investigated the use of menopausal hormone therapy and risk of colorectal cancer.    The study found that Menopausal hormone therapy was associated with overall reduced odds for co...
Restless legs syndrome (RLS) is a condition characterized by discomfort at rest and urge to move focused on the legs. RLS may occur as an idiopathic, often hereditary condition (primary RLS), or in association with medical conditions (secondary RLS) including iron deficiency, uremia, and polyneuropathy. Current understanding of the pathophysio...
The American Journal of GastroenterologyTAKE-HOME MESSAGE In a study evaluating sleep position and nocturnal gastroesophageal reflux, the sleep positions of 57 individuals referred for ambulatory pH impedance were measured and analyzed. The left lateral position was associated with significantly shorter acid exposure time than...
TAKE-HOME MESSAGE A systematic review of the literature published between January 1991 and March 2020 was used to update the 1996 American Academy of Neurology practice parameter that provided considerations for discontinuing antiseizure medications in affected patients.   The authors of this update developed 14 reco...
This clinical practice guideline for the evaluation and diagnosis of chest pain provides recommendations and algorithms for clinicians to assess and diagnose chest pain in adult patients.The “2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain” provides recommendations based on contemporary evidence on...
Conjugated estrogens/bazedoxifene is a selective estrogen receptor modulator. Bazedoxifene stimulates estrogen receptors in bone and has antagonistic effects in the breast and uterus. Conjugated estrogens/bazedoxifene is labeled for the treatment of moderate to severe vasomotor symptoms associated with menopause and prevention of postmenopausal...
Conjugated estrogens/bazedoxifene is a selective estrogen receptor modulator. Bazedoxifene stimulates estrogen receptors in bone and has antagonistic effects in the breast and uterus. Conjugated estrogens/bazedoxifene is labeled for the treatment of moderate to severe vasomotor symptoms associated with menopause and prevention of postmenopausal...
DIET, PHYSICAL ACTIVITY, AND BEHAVIORAL THERAPY Diet, physical activity, and behavioral therapy designed to achieve and maintain >5% weight loss should be prescribed for patients with type 2 diabetes who are overweight or obese and ready to achieve weight loss.    Such interventions should be high intensity (≥16 sessi...