Drugs-for-peptic-ulcer

Gastroenterology: AGA Journal: Published March, 2019Prior research has shown an association between proton pump inhibitors and fracture risk. This study checked for markers for bone reabsorption and formation and followed bone mineral density and the incidence of fractures. It also looked at levels of calcium, magnesium, phosphorous, and parath...
During the holy month of Ramadan, Muslims practice daily fasting from dawn to sunset. This commitment changes their daily food routine in terms of number of meals, quantity of caloric intake, and types of food consumed. This change in consumption patterns during Ramadan has an effect on metabolism and weight, sleeping patterns, and possibly ga...
The Lancet: Published on November, 2022Aspirin is widely recommended for the secondary prevention of thrombotic vascular disease.  Its use is limited principally by increased risk of bleeding, particularly from the gastrointestinal tract.The risks of upper gastrointestinal bleeding can be mitigated in part by acid suppression with proton pump i...
Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency. In Western countries, its incidence was estimated to be over 100 cases per 100 000 adults per year. Fortunately, the mortality rates of AUGIB have decreased over the past few decades, largely attributable to improvements in endoscopic and pharmacological therapies...
Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain. PPI over prescription imposes an economic cost and contri...
The American Journal of Gastroenterology TAKE-HOME MESSAGE This nested case-control study examined adults with gastric, liver, colorectal, and pancreatic cancers and use of PPI for ≥2 years. Cancer risks for PPI dose and duration were also evaluated. While exploratory analysis found an increased cancer risk for PPI use ≥10 years,...
The American Journal of Gastroenterology: Proton pump inhibitors (PPIs) are a class of effective medications used to treat various acid-related disorders. Their use in the clinical setting has increased rapidly and tremendously. PPIs are among the most commonly used medications worldwide. However, the widespread availability of these...
TAKE-HOME MESSAGE The authors investigated physician adherence with recommending peptic ulcer disease (PUD) prophylaxis for elderly patients who were receiving dual antiplatelet therapy or anticoagulation or who were at risk of bleeding PUD, as per expert consensus guidelines from the American College of Gastroenterol...
Peptic ulcer disease is often defined as a mucosal break greater than 3-5 mm in the stomach or duodenum with a visible depth. It is therefore an endoscopic diagnosis in contrast to dyspepsia, which is a clinical diagnosis based on symptoms alone. Peptic ulcer disease results from an imbalance between factors that protect the mucosa of the stoma...
Gastrointestinal (GI) bleeding is the most common GI diagnosis necessitating. Upper GI bleeding (UGIB) refers to bleeding originating from sites in the esophagus, stomach, or duodenum.AbstractThe American Journal of Gastroenterology society performed systematic reviews addressing predefined clinical questions to develop recommendations with the...
A Peptic ulcer is a small sore or lesion in the lining of stomach or duodenum, the first part of the intestine. This sore is often aggravated by stomach acid, but is usually not caused by the acid itself. More likely, the cause is either a bacterium known as Helicobacter pylori (H. pylori) or taking non-steroidal anti-inflammatory drugs (NSAID...
Heartburn is a cardinal symptom of gastro-esophageal reflux disease (GERD) and is among the most common patient complaints.  Chronic GERD can cause heart burn, ulcers, scarring, and inflammation in the esophagus. It can also change cells that line the esophagus. This is known as Barrett's esophagus and it increases the risk of developi...