Disease-information

Guidelines on the Diagnosis of Eosinophilic Oesophagitis in Children and Adults
The British Medical Journal (BMJ): British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines Eosinophilic oesophagitis is a condition characterised by symptoms of dysphagia and/or food impaction in adults, and feeding problems, abdominal...
The safety of Amoxicillin and Clavulanic acid use during the first trimester of Pregnancy
The British Pharmacological Society Journal: Published: 05 September 2019 Penicillin’s are widely used during pregnancy for various bacterial infectious indications. Amoxicillin, rapidly crosses the placenta following absorption to the bloodstream, It is prescribed both as a sole medicine as well as in combination with clavulanic acid mos...
The Effect of the COVID-19 Pandemic on Urine Culture Results and Resistance to Antibiotics
Urinary tract infections (UTIs) represent a common pathology among female patients, leading to overprescribing antibiotics, globally. The emergence of the COVID-19 pandemic has dramatically increased the incidence of this particular viral pneumonia with secondary bacterial superinfection, resulting in continuous therapeutic or prophylactic...
Antacid & Alginate is more effective than antacid in controlling post-prandial oesophageal acid exposure in GERD patients
Heartburn is a cardinal symptom of gastro-oesophageal reflux disease (GERD) and is among the most common patient complaints encountered by physicians. TAKE HOME MESSAGE: This study compared the effect of Antacid & Alginate Liquid to an antacid in controlling post-prandial acid reflux in GERD patients. The current investigation demons...
Amoxicillin-Clavulanic Acid Empirical Oral Therapy for Management of Children with Acute Haematogenous Osteomyelitis
PubMed Central: Published on 2020 August AHOM was defined as any bone infection with a period between symptoms onset and diagnosis < two weeks. AHOM was defined complicated in the presence of sepsis, septic shock, arthritis, cellulitis, sub-periosteal or muscle abscess, deep vein thrombosis pathological fracture, septic emboli or hosp...
Long term impact of prophylactic antibiotic use before incision VS after cord clamping on Children by caesarean section
The British Medical Journal (BMJ): Published 17 May 2022 Compared with vaginal delivery, caesarean section carries a substantially increased risk of maternal postpartum infections. This risk can be reduced by routine provision of prophylactic antibiotics. Evidence from randomized controlled trials shows that antibiotics are more effe...
An update on drug-drug interactions associated with proton pump inhibitors
Expert Opinion on Drug Metabolism & Toxicology Journal: Published on: 11 Jul 2022 Proton pump inhibitors (PPIs) are widely prescribed for the treatment of gastric acid-related disorders and the eradication of Helicobacter pylori. In addition, they are routinely prescribed for the prevention of gastrointestinal bleeding in patients receiv...
Effect of a combination of Telmisartan and Amlodipine on patients with Hypertension
Hypertension is considered a major health problem around the world. It’s associated with increasing risk of mortality due to its complication which has a great impact on patient’s life quality. Chronic uncontrolled hypertension is a significant risk factor for cardiovascular mortality and morbidity, strokes, heart failure, and renal fai...
Dienogest and the Risk of Endometriosis Recurrence Following Surgery
Journal of Minimally Invasive Gynecology: Published on December 2020 Endometriosis is a common condition affecting women of reproductive age, often presenting with pelvic pain and infertility. In addition to significantly impacting a woman’s quality of life, the treatment of endometriosis carries a considerable economic burden. TAKE...
Type 2 Diabetes Mellitus: Outpatient Insulin Management
In patients with type 2 diabetes mellitus, insulin may be used to augment therapy with oral glycemic medications or as insulin replacement therapy.The goals of therapy should be individualized based on many factors, including age, life expectancy, comorbid conditions, duration of diabetes, risk of hypoglycemia, cost, patient motivation, and qu...
Guideline for Treatment of Prolonged Seizures in Children and Adults
American Epilepsy Society issues guideline and treatment algorithm for convulsive status epilepticus. The guideline was endorsed by the Epilepsy Foundation, Child Neurology Society, and American College of Emergency Physicians.Status epilepticus – continuous or rapid sequential seizure activity for 30 minutes or more – is a medical emergency wi...
Treatment of Menopausal Symptoms: An Endocrine Society Clinical Practice Guideline
Hormone therapy is the most effective treatment for vasomotor symptoms (VMS) and other menopausal symptoms. Changing estrogen levels during menopause may impact multiple components involved in maintaining temperature homeostasis.Health care professionals should individualize therapy based on clinical factors and patient preference. They should...