Practice Updates
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BMJ: British Medical Journal: Published September 2024Migraine is a neurological disorder characterized by
disabling, recurrent episodes of moderate to severe headache and accompanying
symptoms lasting up to 72 hours. The acute management of migraine episodes consists of drug
interventions aimed at providing rapid and sustained pain relief, and,...
Antibiotic resistance is one of the greatest public health challenges of
our time—few treatment options exist for people infected with
antibiotic-resistant bacteria.
Journal of the American College of Cardiology: August,
2024Single-pill combinations of 3 or
more low-dose blood pressure (BP)-lowering drugs hold promise for initial or
early treatment of hypertension.The
Authors conducted a placebo-controlled trial of a new single-pill
combination containing low doses of telmisartan, amlodipine, and indapamid...
The American College of
Obstetricians and Gynecologists (ACOG) has provided recommendations for the
treatment of vasomotor and vaginal symptoms related to menopause.Vasomotor and vaginal symptoms
are cardinal symptoms of menopause. Vasomotor symptoms can be particularly
troubling to women and are the most commonly reported menopausal symptoms.M...
Circulation: Cardiovascular Quality and Outcomes: Published
Apr 2024TAKE-HOME MESSAGEThis study
used data from the FAST-MI program to examine the effect of lipid-lowering
therapy (LLT) (atorvastatin ≥40 mg or equivalent or any combination of a statin
and ezetimibe) intensity on long-term mortality in 2258 patients aged 80 years
or older who ex...
Journal of the American Academy of Dermatology: July 2024Male androgenetic alopecia (AGA), or male pattern hair loss,
is characterized by gradual thinning of hair on the vertex of the scalp and
recession of the frontal hairline. FDA-approved therapies are restricted to topical minoxidil
and oral finasteride. Effective non–FDA-approved...
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Instead for viewing the file you can Click here.GO TO DLP SITE
Stepwise Approach of
Dengue Case ManagementPatients Group A: These are patients who are dengue
patients without warning sign and they may be sent home. These patients are
able to tolerate adequate volumes of oral fluids, pass urine at least once
every six hours. Patients Group B: These include patients with warning
signs. These are patients wh...
The Lancet
Diabetes & Endocrinology: Published: March, 2024Atherosclerotic cardiovascular
disease is a leading cause of death worldwide, and LDL cholesterol is a major
causal risk factor.Diabetes substantially increases
the risk of atherosclerotic cardiovascular disease.TAKE-HOME MESSAGEIn this
participant-level meta-analysis of 19 trials, sta...
Take Home Message View All
The British Journal of Dermatology: Published: 16
September 2024Retinoids, widely used in
dermatology for treating acne and various skin conditions, have raised concerns
regarding potential side effects, particularly sexual dysfunction. Although
retinoids are effective in managing skin conditions, their association with sexual
dysfunction is b...
Archives of Dermatological Research: Published: August 2024Vitiligo, an autoimmune condition characterized by
depigmented skin patches due to the loss of functional melanocytes, has been
linked to dysregulation in the JAK-STAT signaling pathway, particularly in
IFN-g signaling. The use of JAK inhibitors, such as ruxolitinib cream, a JAK1
and JA...
Pharmacologic Approaches to
Glycemic Treatment:
The goals
in caring for patients with diabetes mellitus are to eliminate symptoms and to
prevent, or at least slow, the development of complications. FIND BELOW TREATMENT RECOMMENDATIONS FOR TYPE 2 DIABETES:
Disease Highlights View All
Download Dengue Pocket Guideline
The 2020 Global Hypertension Practice Guidelines were developed by the International Society of Hypertension (ISH) Guidelines Committee based on evidence criteria to be used globally. RemoveIn addition to BP control, the therapeutic strategy should include lifestyle changes, body weight control and the effective treatment of the other risk fac...
The Infectious Diseases Society
of America (IDSA) and American Thoracic Society (ATS) issued updated clinical
practice guidelines for community-acquired pneumonia (CAP).Community-acquired pneumonia
(CAP), an infection of the lung parenchyma that occurs in persons outside of a
hospital setting, is associated with high morbidity and mortality.&nb...
Drug Highlights View All
AGA Gastroenterology Journal: Published on November, 2022In adults, obesity-related
complications, such as cardiovascular disease, stroke, type 2 diabetes mellitus
(T2DM), nonalcoholic steatohepatitis, obstructive sleep apnea, osteoarthritis,
and certain types of cancer (eg, colorectal cancer), have also increased,
contributing to high morbidit...
Gastro-esophageal reflux disease
(GERD) is a disorder involving troublesome symptoms associated with persistent reflux
of gastric contents into the esophagus. Symptoms include heartburn, cough,
epigastric pain, vomiting, and regurgitation.GERD is proposed to have 5 distinct
presentations—nonerosive GERD (NERD), erosive esophagitis (EE), functio...
Mycoses Journal: Published on April 2021Dermatomycoses of zoophilic origin,
especially those caused by Trichophyton mentagrophytes, often pose considerable
therapeutic problems. This is reflected in the growing number of strains of
this species with resistance to terbinafine caused by a mutation in the
squalene epoxidase (SQLE) gene. TAKE HOME...