Disease-information

Proton Pump Inhibitors (PPIs) are widely considered the mainstay of medical treatment for GERD. Multiple publications have raised questions about adverse events, raising doubts about the safety of long-term use and increasing concern about overprescribing of PPIs. This guideline provides updated, evidence-based recommendations and practical...
The Journal of Obstetric and Gynecological Research: Miscarriage is the most common cause of early pregnancy loss in the first 24 weeks and one of the most common complications in early pregnancy. An estimated 15% to 20% of pregnancies will end in a miscarriage, with 25% of women experiencing a miscarriage in their lifetime. Women can b...
Endometriosis is defined as the presence of endometrium-like tissue outside the uterus. It causes a chronic inflammatory reaction that may result in the formation of scar tissue (adhesions, fibrosis) within the pelvis and other parts of the body. It is a chronic disease associated with severe, life-impacting pain during periods, sexual...
The British Medical Journal (BMJ): Increasing evidence suggests that reproductive factors unique to women are associated with a greater risk of death from non-communicable diseases. Even if reproductive events do not increase the risk of death from non-communicable diseases, they could be useful as an early stress test of underlying risk...
Indian Journal of Gastroenterology: Published: 30 June 2022 TAKE HOME MESSAGE: Nocturnal acid breakthrough (NAB) may differ based on duration of proton pump inhibitor (PPI) action and Helicobacter pylori (H. pylori) infection; NAB may influence esophageal acidification (EA) and mucosal damage. Dexlansoprazole, a long-acting PPI,...
Successful oocyte implantation and a favorable pregnancy outcome rely on optimal progesterone levels. Therefore, progesterone deficiencies associated with infertility and miscarriages have commonly been treated with progestogens that mimic the activity of progesterone. Among those is dydrogesterone, an oral retrosteroid with a structur...
The Journal of Obstetrics & Gynecology Research: An ovarian endometrioma is a cystic mass arising from ectopic endometrial tissue within the ovary. It contains thick, brown, tar-like fluid, which may be referred to as a "chocolate cyst." Endometriomas are often densely adherent to surrounding structures, such as the peritoneum, fallopian...
PubMed Central: Published on October 2019 Status epilepticus is most common in children younger than 5 years, with incidence between 10 and 60 per 100,000 populations. Convulsive status for 30 min leads to irreversible neuronal injury. TAKE HOME MESSAGE Established Status Epilepticus Treatment Trial proposed that 35%–45% of p...
TAKE-HOME MESSAGEVernal keratoconjunctivitis is a chronic, seasonally exacerbated, allergic inflammation of the eye.This prospective study evaluated the efficacy and safety of montelukast in conjunction with typical topical therapies for treating pediatric vernal keratoconjunctivitis (VKC). Patients were evaluated for subjective improvement in...
Hypertension is one of the leading public health challenges worldwide. It is common in both developed and developing countries. Essential hypertension is believed to be a result of complex interaction of genetic and environmental factors. Increased peripheral resistance is responsible for most of the cases of essential hypertension....
GERD is associated with substantial reductions in subjective well-being, lower work productivity, and increased healthcare use. The GERD in the Asia Pacific Survey (GAPS) found that GERD had a negative impact on well-being for 94% of respondents in terms of stress (68% of respondents), restrictions to daily activities (50%), and reduced wor...
Global Journal of Reproductive Medicine: Endometriosis is a common disease in up to 10% of women of reproductive age. It often causes symptoms such as dysmenorrhea, chronic pelvic pain, dyspareunia and dyschezia. It is also associated with ovarian endometrioma which requires surgery for both diagnosis and treatment. However, recurrence r...