Disease-information

PubMed Central: IntroductionThreatened miscarriage is a common disease during early pregnancy, with a morbidity of 30% to 40%, which could develop into a complete miscarriage or dystocia without timely treatment. Many pathogenic factors contribute to the threatened miscarriage, of which lacking progestogens due to the endocrine dysfunction of...
Gastroesophageal reflux disease (GERD) and idiopathic pulmonary fibrosis (IPF) are two pathological conditions often strictly related, even if a clear relationship of causality has not been demonstrated. GERD is a frequent comorbidity in IPF patients, as demonstrated using combined multichannel intraluminal impedance-pH, despite being...
Key Information: Progesterone is essential for the maintenance of a healthy pregnancy. Progesterone is frequently prescribed to patients presenting with per vaginal (PV) bleeding in early pregnancy and a history of recurrent pregnancy loss. Any defect in the secretion of human chorionic gonadotropin or progesterone is associated with...
Key Information: Progesterone is essential for the maintenance of a healthy pregnancy. Progesterone is frequently prescribed to patients presenting with per vaginal (PV) bleeding in early pregnancy and a history of recurrent pregnancy loss. Any defect in the secretion of human chorionic gonadotropin or progesterone is associated with...
Take Home Message: Endometriosis is estimated to affect 10–15% of women of childbearing age and as much as 15–30% of those with primary or secondary infertility. Endometriosis associated pelvic pain (EAPP) is the most common complaint of patients with endometriosis. It occurs when endometrial cells proliferate outside the uterus, for...
Alimentary Pharmacology & Therapeutics: Functional dyspepsia is characterised by troublesome early satiety, fullness, or epigastric pain or burning. It can easily be overlooked as the symptoms overlap with gastro-oesophageal reflux disease and irritable bowel syndrome. It affects 10% of the population and is more prevalent in women....
Combined oral contraceptives (COC) and progestogens are widely used for the treatment of endometriosis. TAKE HOME MESSAGE This study was carried out to compare the effect of dienogest (2mg) vs a combined oral contraceptive (levonorgestrel 0.1mg/ethinyl estradiol 0.02mg) on ovarian endometriomas, deep infiltrating endometriosis (DIE),...
Proton Pump Inhibitors (PPIs) are widely considered the mainstay of medical treatment for GERD. Multiple publications have raised questions about adverse events, raising doubts about the safety of long-term use and increasing concern about overprescribing of PPIs. This guideline provides updated, evidence-based recommendations and practical...
The Journal of Obstetric and Gynecological Research: Miscarriage is the most common cause of early pregnancy loss in the first 24 weeks and one of the most common complications in early pregnancy. An estimated 15% to 20% of pregnancies will end in a miscarriage, with 25% of women experiencing a miscarriage in their lifetime. Women can b...
Endometriosis is defined as the presence of endometrium-like tissue outside the uterus. It causes a chronic inflammatory reaction that may result in the formation of scar tissue (adhesions, fibrosis) within the pelvis and other parts of the body. It is a chronic disease associated with severe, life-impacting pain during periods, sexual...
The British Medical Journal (BMJ): Increasing evidence suggests that reproductive factors unique to women are associated with a greater risk of death from non-communicable diseases. Even if reproductive events do not increase the risk of death from non-communicable diseases, they could be useful as an early stress test of underlying risk...
Indian Journal of Gastroenterology: Published: 30 June 2022 TAKE HOME MESSAGE: Nocturnal acid breakthrough (NAB) may differ based on duration of proton pump inhibitor (PPI) action and Helicobacter pylori (H. pylori) infection; NAB may influence esophageal acidification (EA) and mucosal damage. Dexlansoprazole, a long-acting PPI,...