Disease-information

The Lancet: Published on September, 2022A promising malaria vaccine was up to 80% effective at preventing the disease in young children who received a booster shot at one year following a primary three-dose regime maintained high efficacy against malaria, and continued to meet the World Health Organization’s Malaria Vaccine Technology Roadmap g...
Journal of the American Heart Association (AHA): Published on November, 2022Sleep, alongside diet and physical activity (PA), is one of the 3 pillars of health, but unlike other health behaviors, healthy sleep is not included in the American College of Cardiology/American Heart Association (AHA) cardiovascular disease (CVD) prevention guideline...
Nature Medicine: Published on November, 2022Obesity is a chronic, relapsing disease with a substantial morbidity, mortality, and healthcare burden. Drug interventions for the treatment of obesity provide a potential valuable adjunct to lifestyle interventions, which often achieve only limited weight loss that is difficult to maintain. Semagluti...
The Journal of Clinical Endocrinology and Metabolism (JCEM): Published On October, 2022Nonalcoholic fatty liver disease (NAFLD) is associated with obesity and type 2 diabetes (T2D), causing substantial burden from hepatic and extrahepatic complications.TAKE-HOME MESSAGEThis review discusses practical approaches to the management of patients wit...
Journal of the American College of Cardiology: Published on December, 2022Healthy dietary patterns are rich in micronutrients, but their influence on cardiovascular disease (CVD) risks has not been systematically quantified.The goal of this study was to provide a comprehensive and most up-to-date evidence-based map that systematically quantifi...
MIDDLE EAST JOURNAL OF FAMILY MEDICINE: Published on November, 2022A Systematic Review and Meta-AnalysisEndometriosis is a chronic, estrogen-dependent disease that affects 10-15% of women in their reproductive age. It is characterized by the presence of endometriallike tissues outside the uterine cavity that induce chronic inflammation, ovarian...
Journal of Clinical Medicine: Published on November 2022Periodontitis is an inflammatory disease of multifactorial origin, characterized by periods of exacerbation and remission. The main etiological factors for the disease include gram-negative anaerobic bacteria and a variety of facultative bacteria that reside in the subgingival biofilm.Var...
JAMA Pediatrics: Published on November 2022A Systematic Review and Meta-analysisTAKE-HOME MESSAGEAre shorter courses of antibiotics as good as longer courses?This systematic review and meta-analysis assessed whether shorter courses of antibiotics are noninferior to longer courses of antibiotics for nonsevere community-acquired pneumonia (CAP) in...
JAMA Pediatrics: Published on November 2022A Systematic Review and Meta-analysisTAKE-HOME MESSAGEAre shorter courses of antibiotics as good as longer courses?This systematic review and meta-analysis assessed whether shorter courses of antibiotics are noninferior to longer courses of antibiotics for nonsevere community-acquired pneumonia (CAP) in...
Diabetes Care: Published on December 2022With the numbers of people with type 2 diabetes rising worldwide, dietary modifications provide an essential therapeutic approach for blood glucose, weight, and cardiovascular risk-factor management. Intermittent fasting (IF) has emerged as an alternative to classic daily caloric reduction. The approache...
The Lancet: Published on January, 2023The appropriate duration of postoperative antibiotics for complex appendicitis is unclear. The increasing global threat of antimicrobial resistance warrants restrictive antibiotic use, which could also reduce side-effects, length of hospital stay, and costs.TAKE-HOME MESSAGEThis pragmatic, open-label, rando...
ACP Journals: Annals of Internal Medicine: Published on February 2023In this systematic review and meta-analysis, the authors assessed whether vitamin D administration decreases the risk for diabetes in individuals with prediabetes. TAKE-HOME MESSAGECombining data from three randomized trials, the authors demonstrated that vitamin D reduced the...