Disease-information
Updated Systematic Review and Meta-analyses:Bipolar disorder (formerly called manic depression) is a mood
disorder characterized by periods of depression and periods of
abnormally-elevated mood.Valproate is an anticonvulsant drug that is frequently used
in maintenance treatment of bipolar disorder. Clinicians and patients should
consider accept...
Parkinson's disease (PD) is a progressive, neurodegenerative
disorder of aging that affects both motor and cognitive function. The etiology
of PD is mostly unknown, but it likely involves both genetic and environmental
factors.Recognizing early symptoms of Parkinson'sNonmotor symptoms:Nonmotor symptoms are common in early Parkinson disease. The...
A Report
of the American Academy of Neurology (AAN) Guideline Subcommittee:Levodopa preferred as initial dopaminergic therapy for motor symptoms in
patients with early Parkinson disease.Parkinson
disease (PD) is a neurodegenerative disorder that causes both motor and
nonmotor symptoms and increases in prevalence with age. Motor symptoms in the...
Studies clarify menopausal HT’s impact on breast cancer riskOne of the greatest concerns of women who are considering
Menopausal Hormone Therapy (MHT) is the relationship between hormone use and
breast cancer. Data from the The Women’s Health Initiative (WHI) suggest an
increase in risk with combined estrogen-progestin therapy, but a reduction i...
Studies clarify menopausal HT’s impact on breast cancer riskOne of the greatest concerns of women who are considering
Menopausal Hormone Therapy (MHT) is the relationship between hormone use and
breast cancer. Data from the The Women’s Health Initiative (WHI) suggest an
increase in risk with combined estrogen-progestin therapy, but a reduction i...
JAMA Internal MedicineTAKE-HOME MESSAGEThis retrospective study evaluated
the association between statin initiation and diabetes progression. Progression
of diabetes occurred in significantly more statin users. There was a
dose–response relationship with higher-intensity statin use.The study examined 12 years of data
on patients covered by the...
JAMA Internal MedicineTAKE-HOME MESSAGEThis retrospective study evaluated
the association between statin initiation and diabetes progression. Progression
of diabetes occurred in significantly more statin users. There was a
dose–response relationship with higher-intensity statin use.The study examined 12 years of data
on patients covered by the...
JAMA NeurologyTAKE-HOME MESSAGE
Evidence is rapidly accumulating of
the benefit of exercise and physical activity in Parkinson disease (PD). The
authors conducted a nationwide population-based cohort study of 10,699
individuals with PD, evaluating the association of physical activity (obtained
from self-reported structured questionnaires...
Generalized anxiety disorder (GAD)
is the most common mental disorders. The hallmark of GAD is excessive,
out-of-control worry. This condition can negatively impact a patient's quality of
life and disrupt important activities of daily living. Women are twice as
likely as men to have the disorder. It often begins in childhood or adolescence...
Generalized anxiety disorder (GAD)
is the most common mental disorders. The hallmark of GAD is excessive,
out-of-control worry. This condition can negatively impact a patient's quality of
life and disrupt important activities of daily living. Women are twice as
likely as men to have the disorder. It often begins in childhood or adolescence...
Journal of the American Medical
Association (JAMA)
SurgeryTranexamic
acid is an antifibrinolytic compound which inhibits fibrinolysis by blocking
the binding of plasminogen and plasmin to fibrin, thus preventing dissolution
of the haemostatic plug.
TAKE-HOME MESSAGE
Question Is
intravenous administration of tranexamic acid associated wi...
Motor symptoms are those that
affect movement of the body. These are the cardinal symptoms of PD. The main
motor symptoms of PD are tremor, slowness of movement (bradykinesia), stiffness
(rigidity), and poor balance (postural instability). These symptoms are usually
mild in the early stages of the disease. PD patients show additional mo...
