Disease-information

Outcomes in Children of Women with Type 2 Diabetes Exposed to Metformin vs Placebo during Pregnancy
The Lancet Diabetes & Endocrinology: Published on February, 2023Metformin is increasingly being used during pregnancy, with potentially adverse long-term effects on children. This study aimed to examine adiposity in children of women with type 2 diabetes from the Metformin in Women with Type 2 Diabetes in Pregnancy (MiTy) trial, with and withou...
Outcomes in Children of Women with Type 2 Diabetes Exposed to Metformin vs Placebo during Pregnancy
The Lancet Diabetes & Endocrinology: Published on February, 2023Metformin is increasingly being used during pregnancy, with potentially adverse long-term effects on children. This study aimed to examine adiposity in children of women with type 2 diabetes from the Metformin in Women with Type 2 Diabetes in Pregnancy (MiTy) trial, with and withou...
Antibiotic use as a risk factor for inflammatory bowel disease across the ages
BMJ Journals: Gut: Published on March, 2023Inflammatory bowel disease (IBD) is a chronic immune-mediated disease of the bowel, comprising two main subtypes: Crohn’s disease (CD) and ulcerative colitis (UC).There is an increasing incidence of inflammatory bowel disease (IBD) for which environmental factors is suspected. Antibiotics have been ass...
Effect of SGLT2 Inhibitors on Kidney and CV Events in Patients with Advanced Diabetic Kidney Disease
Diabetes Research and Clinical Practice: Published on December, 2022Sodium-Glucose Transport Protein 2 (SGLT2) Inhibitors also called gliflozins are a class of medicine used to lower high blood glucose levels in people with type 2 diabetes. Medicines in the SGLT2 inhibitor class include Canagliflozin, Dapagliflozin, Empagliflozin, Ertugli...
Luliconazole: Newer antifungals Shorten Tinea Pedis Treatment Duration, Promote Adherence
FRONTLINE MEDICAL NEWS – Dr. Boni E. Elewski.Luliconazole (NULIZA ®) has something unique to offer when it comes to treating tinea pedis. This is an azole drug, meaning it is broad spectrum and kills dermatophytes, yeast, and molds. Also, like all azoles, it has some antibacterial activity. The generic Luliconazole (NULIZA ®) is approved f...
Duration of Antibiotic Treatment for Gram-Negative Bacteremia
eClinicalMedicine Journal: The LANCET: Published on December, 2022Gram-negative bacteremia is common in both community and health care settings, with a significant increase in incidence described for some Gram-negative bacteria in recent years.Prolonged duration of antibiotic therapy for such common infections may lead to increased resistance em...
Chlorthalidone vs Hydrochlorothiazide for Hypertension-Related Cardiovascular Events
The New England Journal of Medicine: Published on December, 2022Hypertension increases the risk of complications and death from cardiovascular disease. Thiazide diuretics are first-line antihypertensive agents that lower blood pressure and prevent adverse cardiovascular outcomes. Early studies suggested that chlorthalidone was superior to hydro...
Elagolix: a promising oral GnRH antagonist for endometriosis-associated pain
The New England Journal of Medicine (NEJM): Published on July 6, 2017 Endometriosis is a chronic, estrogen-dependent, inflammatory condition that is characterized by the implantation of endometrial-like tissue outside the uterus and affects 6 to 10% of women of reproductive age. Symptoms: Endometriosis symptoms include dysmenorrhe...
Long-Term Safety of Elagolix with Hormonal Add-Back Therapy in Women with Endometriosis-Associated Pain: 24-Month Results
American College of Obstetricians and Gynecologists (ACOG): Published on May 2022TAKE HOME MESSAGE:Endometriosis is a benign uterine disorder characterized by menstrual pain and infertility, deeply affecting women’s health. It is a chronic disease and requires a long term management. Hormonal drugs are currently the most used for the medical tr...
Outcomes of subchorionic hematoma-affected pregnancies in the infertile population
International Journal of Gynecology & Obstetrics: Published on February 2022A subchorionic hematoma (SCH) is a common finding on obstetric ultrasounds, and the prevalence is often higher among the infertile population—affecting between 18%–40% of those pregnancies in recent studies. SCHs are collections of fluid seen on ultrasound between the...
Idiopathic pulmonary fibrosis and gastroesophageal reflux disease (GERD)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibroinflammatory lung disease associated with increased morbidity and mortality. As its name suggests, the exact cause of the disease is not known. However, some genetic and environmental factors have been observed concurrently with the condition and are considered potential etiolo...
Idiopathic pulmonary fibrosis and gastroesophageal reflux disease (GERD)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibroinflammatory lung disease associated with increased morbidity and mortality. As its name suggests, the exact cause of the disease is not known. However, some genetic and environmental factors have been observed concurrently with the condition and are considered potential etiolo...