Disease-information

Levetiracetam versus Phenobarbitone in Neonatal Seizures
Seizures are the most common manifestation of neurological insult during the neonatal period. The most common cause of symptomatic neonatal seizures is hypoxic/ischemic encephalopathy (HIE) which affects approximately 1-2/100 live births.There are no evidence-based guidelines for the pharmacologic treatment of neonatal seizures and management...
Montelukast and Budesonide combination for children with Chronic Cough-Variant Asthma
Chronic cough-variant asthma (CCVA) is a very common subtype of bronchial asthma among children population. This condition often manifests with acute cough, chronic cough, and intractable cough, especially at night. It has been reported that CCVA contributed 24.0% to 33.3% of chronic cough cases, and children alone accounted for the incidence o...
Montelukast and Budesonide combination for children with Chronic Cough-Variant Asthma
Chronic cough-variant asthma (CCVA) is a very common subtype of bronchial asthma among children population. This condition often manifests with acute cough, chronic cough, and intractable cough, especially at night. It has been reported that CCVA contributed 24.0% to 33.3% of chronic cough cases, and children alone accounted for the incidence o...
Sequential treatment with Empagliflozin and Linagliptin is an effective treatment option in people with type 2 diabetes receiving Metformin
Diabetes, Obesity and Metabolism Journal: PubMedTAKE HOME MESSAGE:The study aims to investigate the effect of sequential treatment escalation with empagliflozin and linagliptin on laboratory markers of α- and β-cell function in people with type 2 diabetes mellitus (T2DM) insufficiently controlled on metformin monotherapy.The researchers found t...
Reductions in endometriosis-associated pain in women treated with Elagolix are consistent in various demographics or medical histories
Endometriosis can be asymptomatic; women often experience a range of symptoms with dysmenorrhea, non-menstrual pelvic pain (NMPP), and dyspareunia being more common; other symptoms include constipation, dyschezia, dysuria, and infertility. For many women, the burden of symptoms associated with endometriosis also reduces quality of life and profound...
Levetiracetam, Fosphenytoin, and Valproate for Status Epilepticus patients who do not respond to Benzodiazepines
The New England Journal of Medicine: Published on December, 2019Evidence supports the use of benzodiazepines as the initial treatment for status epilepticus; however, seizures do not respond to benzodiazepines in up to a third of patients. Of the three medications most commonly used to treat benzodiazepine-refractory status epilepticus — leveti...
Treatment for Mild Chronic Hypertension during Pregnancy
The New England Journal of Medicine (NEJM): Published on April, 2022Antihypertensive treatment during pregnancy reduces the frequency of severe hypertension (blood pressure, ≥160/110 mm Hg) but has not been shown to improve maternal, fetal, or neonatal outcomes and has been associated with an increased risk of small-for-gestational-age birth w...
Treatment for Mild Chronic Hypertension during Pregnancy
The New England Journal of Medicine (NEJM): Published on April, 2022Antihypertensive treatment during pregnancy reduces the frequency of severe hypertension (blood pressure, ≥160/110 mm Hg) but has not been shown to improve maternal, fetal, or neonatal outcomes and has been associated with an increased risk of small-for-gestational-age birth w...
Diagnosis and Management of Hand Foot and Mouth Disease (HFMD)
Hand-foot-and-mouth disease (HFMD) is a common but highly contagious acute viral infection due to an enterovirus infection. The disease is most common under the age of 10, and most are under 5 years of age (95%). It can uncommonly affect adults and tends to be more severe in the elderly, immunocompromised, and pregnant women.  What is the cause...
Recent Outbreak of Viral Conjunctivitis: Diagnosis and Management
Conjunctivitis is one of the most common causes of red-eye and affects patients of all ages and socioeconomic class. Viral conjunctivitis is responsible for the majority of infectious conjunctivitis, accounting for up to 75% of cases and is more prevalent in the summer.What is conjunctivitis?Conjunctivitis, also known as "pink eye", is inflam...
Elevated Dengue fever activity reported at Dhaka & Chattogram: Clinical Manifestation and Diagnosis of Dengue Fever
Dengue is endemic in Bangladesh with recurrent outbreaks.  Health officials in Bangladesh have reported elevated dengue fever activity in Bangladesh during 2022. Dhaka and Chattogram has become a hotspot for dengue fever (DF).Why DF rising in August & September?•       The risk of dengue fever transmission in Bangladesh exists nationwide and...
WHO Guideline for the pharmacological treatment of Hypertension
The 2021 WHO hypertension guideline aims to provide the most current and relevant evidence based global public health guidance on the initiation of treatment (with pharmacological agents) for hypertension in adults. The recommendations target adult, non-pregnant patients who were appropriately diagnosed with hypertension and counseled about li...