Disease-information
Hypothyroidism is a common
endocrine disorder resulting from deficiency of thyroid hormone. Iodine
deficiency remains the most common cause of hypothyroidism worldwide.The most common symptoms in adults
are fatigue, lethargy, cold intolerance, weight gain, constipation, depression,
change in voice, and dry skin, but clinical presentation can di...
The Journal of Urology:Clomipramine is a tricyclic
antidepressant (TCA) that has been found effective at a daily dose of 25 mg or
50 mg for premature ejaculation (PE) in multiple studies. Additionally, TCAs can carry
significant side effects such as dizziness, dry mouth, and constipation. As a result, on-demand treatment is
greatly preferred, e...
Dengue is the most common
mosquito-borne, viral disease in the world. Dengue virus is a single stranded
positive polarity RNA virus, belongs to the family Flaviviridae. The Den-2 and Den-3 variants of
dengue are active this year and of the two, Den-2 is more prominent, according
to the Institute of Epidemiology, Disease Control and Researc...
The British Journal of DermatologyDermatophytic infections have
undergone unprecedented changes in India in the recent past. Oral antifungal drugs are
considered to have a high cure rate in tinea corporis, tinea cruris and tinea
faciei.Clinical trials to find out the
effectiveness of the four main oral antifungal drugs are lacking.Authors teste...
JAMA Network: November, 2019Proton pump inhibitors (PPIs) are
drugs widely prescribed to reduce gastric acidity. Although they are considered
globally safe, observational studies have reported significant
adverse effects associated with their long-term use, such as
osteoporotic-related fractures, vitamin B12 deficiency, kidney
disease, or...
Superficial fungal infections are primarily caused by
dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the
world’s population.The lesion of dermatophytosis is present with an annular or
ring-shaped red scaly plaque with central clearing, often associated with
severe pruritus.Systemic or topical antifungal drugs are used as...
JAMA Internal Medicine: Published on May, 2023Diabetic kidney disease is the leading cause of chronic
kidney disease and end-stage kidney failure in the vast majority of the
world. TAKE-HOME MESSAGEThis randomized clinical trial evaluated the use of
glucose-lowering medications on kidney outcomes. A total of 5047 patients with type 2 diabet...
Clinicians should be more judicious in prescribing or
recommending oral or topical antifungal therapy.Given the limited selection of antifungals, it is paramount
to mitigate resistant cases. Mitigation proposals include:·
good
skin hygiene,· &nb...
Obstetrics and Gynecology Journal: Published on October 2021Endometriosis affects 6–10% of reproductive-aged women and is
associated with significant morbidity.Clinical manifestations are broad and can include
dysmenorrhea, nonmenstrual pelvic pain, dyspareunia, dyschezia, and
infertility. The wide range of presentations hinder the ability...
AACE Endocrine Practice Journal: Published
on May, 2022Nonalcoholic fatty liver disease
(NAFLD) is part of a multisystemic disease and is closely associated with
obesity, insulin resistance (IR), type 2 diabetes mellitus (T2D), hypertension,
and atherogenic dyslipidemia. The definition of NAFLD is based on
the presence of hepatic steatosis in...
International Journal of Research in Dermatology: Published
on February, 2021Dermatophytic infections are the
most prevalent fungal infections, which affect majority of the global
population. Indian climate, especially the hot and humid conditions contribute
majorly to dermatophytosis. Azoles are the most commonly used
antifungal agents due t...
OVERVIEWTotal official hospitalizations in
Bangladesh were 2,573 since January, 2023 according to a press release of the
Directorate General of Health Services.Of the total hospitalization this
year, 1,870 were reported in Dhaka city and 703 in other places outside the
Dhaka city. The mosquito-borne viral disease killed 17 people so far this ye...
