Disease-information

Diabetes Journal: ADA publications Several randomized clinical trials have shown the possibility of preventing or delaying the onset of type 2 diabetes in nondiabetic adults at high risk of developing the disease. Successful interventions have included drugs (not further discussed here) and lifestyle interventions emphasizing weight loss...
TAKE HOME MESSAGE Acute pharyngitis is one of the most common complaints that a physician encounters in the ambulatory care setting, accounting for 1% to 2% of all ambulatory care visits annually and a high antibiotic prescribing rate. However, the majority of these cases is viral and is self-limiting even in cases caused by bacteria...
TAKE HOME MESSAGE Acute pharyngitis is one of the most common complaints that a physician encounters in the ambulatory care setting, accounting for 1% to 2% of all ambulatory care visits annually and a high antibiotic prescribing rate. However, the majority of these cases is viral and is self-limiting even in cases caused by bacteria...
The American Journal of Gastroenterology TAKE-HOME MESSAGE This nested case-control study examined adults with gastric, liver, colorectal, and pancreatic cancers and use of PPI for ≥2 years. Cancer risks for PPI dose and duration were also evaluated. While exploratory analysis found an increased cancer risk for PPI use ≥10 years,...
The Pediatric Infectious Disease Journal: Clostridium difficile is an important cause of antibiotic-associated diarrhea and the most widely recognized diarrheal pathogen acquired in healthcare settings. Antibiotic or gastric acid suppressant exposure, gastrointestinal feeding devices, and certain medical conditions, such as malign...
The Pediatric Infectious Disease Journal: Clostridium difficile is an important cause of antibiotic-associated diarrhea and the most widely recognized diarrheal pathogen acquired in healthcare settings. Antibiotic or gastric acid suppressant exposure, gastrointestinal feeding devices, and certain medical conditions, such as malign...
Proton pump inhibitors (PPIs) have been widely used for decades to treat acid-related diseases. PPIs exhibit a well-established safety profile and reduce gastric acid more effectively than histamine-2 receptor antagonists or antacids. However, observational studies suggest that long-term PPI therapy is associated with osteoporotic fract...
Journal of Oral and Maxillofacial Surgery: Odontogenic infections are a common problem in dentistry, and their treatment often requires the use of antibiotics besides the removal of the source of infection, which frequently makes it more difficult for clinicians to make a decision regarding the choice of antibiotic. The pathogenesis...
Key Information In the last decade, gastro-esophageal reflux disease (GERD) and its complications of Barrett's oesophagus and oesophageal adenocarcinoma are increasingly prevalent, especially in Asia. The rise in GERD among Asians is largely attributed to a recent increase in the prevalence of obesity. Physiological dysfunction of the...
Key Information: Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality globally in preschool children with acute lower respiratory infections. Current guidelines do not support the routine use of antibiotics in these children. However, higher incidence of bacterial co-infection with RSV bronchopulmonary infe...
Key Information: Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality globally in preschool children with acute lower respiratory infections. Current guidelines do not support the routine use of antibiotics in these children. However, higher incidence of bacterial co-infection with RSV bronchopulmonary infe...
JAMA Network: A Systematic Review and Meta-analysis Osteoporosis is characterized by reduced bone mass and fragmentation of bone architecture, resulting in an increased risk of fracture. Approximately 1 in 2 women and 1 in 5 men aged 50 years or older will experience an osteoporotic fracture in their remaining lifetime. Hip fracture is...