Disease-information

The Pediatric Infectious Disease Journal: Clostridium difficile is an important cause of antibiotic-associated diarrhea and the most widely recognized diarrheal pathogen acquired in healthcare settings. Antibiotic or gastric acid suppressant exposure, gastrointestinal feeding devices, and certain medical conditions, such as malign...
Proton pump inhibitors (PPIs) have been widely used for decades to treat acid-related diseases. PPIs exhibit a well-established safety profile and reduce gastric acid more effectively than histamine-2 receptor antagonists or antacids. However, observational studies suggest that long-term PPI therapy is associated with osteoporotic fract...
Journal of Oral and Maxillofacial Surgery: Odontogenic infections are a common problem in dentistry, and their treatment often requires the use of antibiotics besides the removal of the source of infection, which frequently makes it more difficult for clinicians to make a decision regarding the choice of antibiotic. The pathogenesis...
Key Information In the last decade, gastro-esophageal reflux disease (GERD) and its complications of Barrett's oesophagus and oesophageal adenocarcinoma are increasingly prevalent, especially in Asia. The rise in GERD among Asians is largely attributed to a recent increase in the prevalence of obesity. Physiological dysfunction of the...
Key Information: Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality globally in preschool children with acute lower respiratory infections. Current guidelines do not support the routine use of antibiotics in these children. However, higher incidence of bacterial co-infection with RSV bronchopulmonary infe...
Key Information: Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality globally in preschool children with acute lower respiratory infections. Current guidelines do not support the routine use of antibiotics in these children. However, higher incidence of bacterial co-infection with RSV bronchopulmonary infe...
JAMA Network: A Systematic Review and Meta-analysis Osteoporosis is characterized by reduced bone mass and fragmentation of bone architecture, resulting in an increased risk of fracture. Approximately 1 in 2 women and 1 in 5 men aged 50 years or older will experience an osteoporotic fracture in their remaining lifetime. Hip fracture is...
JAMA Surgery: Surgical site infections (SSIs) are infections of the incision or organ or space that occur after surgery. Surgical patients initially seen with more complex comorbidities and the emergence of antimicrobial-resistant pathogens increase the cost and challenge of treating SSIs. The prevention of SSI is increasingly important...
Osteoporosis is a bone disorder that increases a person’s risk of fracture due to low bone mineral density (BMD), impaired bone microarchitecture/mineralization, and/or decreased bone strength. Osteoporotic fractures most commonly occur at the hip, spine and wrist. Fracture prevalence increases dramatically with age. The majority of pos...
European Heart Journal: Emerging as a new epidemic, long COVID or post-acute sequelae of coronavirus disease 2019 (COVID-19), a condition characterized by the persistence of COVID-19 symptoms beyond 3 months. The long-term impact of COVID-19 on cardiovascular (CV) health and mortality is also emerging as a major global concern. Definit...
BioMed Central (BMC) Gastroenterology Journal: Gastroesophageal reflux disease (GERD) is one the most common medical complaints in pregnant women. Its prevalence has been reported to reach as high as 80% in certain populations. The prevalence of GERD is also increased as pregnancy progresses from the first to third trimester. Some women...
European Heart Journal: Worldwide, survivors of COVID-19 now exceed hundreds of millions, with some reporting incomplete recovery months beyond the acute illness, a condition commonly referred to as long COVID. Persistent symptoms of breathlessness, chest pain, fatigue, headaches, brain fog, and palpitations are a constant reminder of th...