Disease-information
The American Journal of Gastroenterology
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This nested case-control study
examined adults with gastric, liver, colorectal, and pancreatic cancers and use
of PPI for ≥2 years. Cancer risks for PPI dose and duration were also
evaluated.
While exploratory analysis found
an increased cancer risk for PPI use ≥10 years,...
The Pediatric Infectious
Disease Journal:
Clostridium difficile is an important cause of
antibiotic-associated diarrhea and the most widely recognized diarrheal
pathogen acquired in healthcare settings.
Antibiotic or gastric acid suppressant exposure, gastrointestinal feeding
devices, and certain medical conditions, such as malign...
The Pediatric Infectious
Disease Journal:
Clostridium difficile is an important cause of
antibiotic-associated diarrhea and the most widely recognized diarrheal
pathogen acquired in healthcare settings.
Antibiotic or gastric acid suppressant exposure, gastrointestinal feeding
devices, and certain medical conditions, such as malign...
Proton
pump inhibitors (PPIs) have been widely used for decades to treat acid-related
diseases. PPIs exhibit a well-established safety profile and reduce gastric
acid more effectively than histamine-2 receptor antagonists or antacids.
However,
observational studies suggest that long-term PPI therapy is associated with
osteoporotic fract...
Journal of Oral and Maxillofacial Surgery:
Odontogenic infections are a common
problem in dentistry, and their treatment often requires the use of antibiotics
besides the removal of the source of infection, which frequently makes it more
difficult for clinicians to make a decision regarding the choice of antibiotic.
The pathogenesis...
Key Information
In the last decade, gastro-esophageal
reflux disease (GERD) and its complications of Barrett's oesophagus and
oesophageal adenocarcinoma are increasingly prevalent, especially in Asia. The
rise in GERD among Asians is largely attributed to a recent increase in the
prevalence of obesity.
Physiological dysfunction of the...
Key Information:
Respiratory
syncytial virus (RSV) is a leading cause of morbidity and mortality globally in
preschool children with acute lower respiratory infections.
Current
guidelines do not support the routine use of antibiotics in these children. However, higher incidence of bacterial co-infection with RSV
bronchopulmonary infe...
Key Information:
Respiratory
syncytial virus (RSV) is a leading cause of morbidity and mortality globally in
preschool children with acute lower respiratory infections.
Current
guidelines do not support the routine use of antibiotics in these children. However, higher incidence of bacterial co-infection with RSV
bronchopulmonary infe...
JAMA Network: A Systematic Review
and Meta-analysis
Osteoporosis is characterized by
reduced bone mass and fragmentation of bone architecture, resulting in an
increased risk of fracture. Approximately 1 in 2 women and 1 in 5 men aged 50
years or older will experience an osteoporotic fracture in their remaining lifetime.
Hip fracture is...
JAMA Surgery:
Surgical
site infections (SSIs) are infections of the incision or organ or space that
occur after surgery. Surgical patients initially seen with more
complex comorbidities and the emergence of antimicrobial-resistant pathogens
increase the cost and challenge of treating SSIs. The prevention of SSI is
increasingly important...
Osteoporosis is a bone disorder
that increases a person’s risk of fracture due to low bone mineral density
(BMD), impaired bone microarchitecture/mineralization, and/or decreased bone
strength. Osteoporotic fractures most commonly occur at the hip, spine and
wrist.
Fracture prevalence increases
dramatically with age. The majority of pos...
European Heart Journal:
Emerging as a new epidemic, long COVID or post-acute sequelae
of coronavirus disease 2019 (COVID-19), a condition characterized by the
persistence of COVID-19 symptoms beyond 3 months. The long-term impact of COVID-19 on cardiovascular (CV) health and
mortality is also emerging as a major global concern.
Definit...
