Endocrine-disorders
Diabetes, Obesity &
Metabolism Journal: Published:
December 2023Type 2 diabetes (T2D) and liver diseases are closely
associated. T2D is an independent risk factor for chronic liver diseases,
including metabolic dysfunction-associated steatotic liver disease (MASLD),
non-alcoholic steatohepatitis, cirrhosis and hepatocellular carcinoma...
The Lancet Diabetes
& Endocrinology: Published
December, 2023Inflammation has been implicated in the pathogenesis of
diabetes. This study investigated the randomised treatment effect of low-dose
aspirin on incident type 2 diabetes and fasting plasma glucose (FPG)
concentrations among older adults.TAKE-HOME MESSAGEThis post hoc analysis of...
Journal of Diabetes and its Complications: September
2023Kidney disease is a diabetes-related
complication and diabetes is the most common cause of end-stage kidney disease
(ESKD) in the world.This study analyzed the incidence of kidney disease in the
Diabetes Prevention Program Outcomes Study.TAKE-HOME MESSAGEAfter 21
years of randomization i...
Diabetes Care Journal (ADA): August, 2023Early identification of patients
with type 2 diabetes who are at risk of kidney disease progression is
particularly important in the context of new glucose-lowering medications such
as sodium-glucose cotransporter 2 (SGLT2) inhibitor (Dapagliflozin, Canagliflozin,
Empagliflozin, Ertugliflozin) that can m...
TAKE HOME MESSAGERequests
for thyroid tests are increasing, although in many cases clinical need is not
evident.If thyroid
dysfunction is suspected, measuring TSH alone is recommended as the first step.
Test T4 only when TSH is abnormal.Ultrasound
should be considered for patients with thyroid dysfunction and goitre (enlarged
thyroid) or palp...
ADA Journal: Diabetes Care: July, 2023Diabetes can be diagnosed by demonstrating increased
concentrations of glucose in venous plasma or increased hemoglobin A1c (HbA1c)
in the blood. Glycemic control is monitored by the people with diabetes
measuring their own blood glucose with meters and/or with continuous
interstitial glucose monitorin...
JAMA: The Journal of the American Medical Association: July, 2019Subclinical hypothyroidism, defined
as an elevated serum thyrotropin (often referred to as thyroid-stimulating
hormone, or TSH) level with normal levels of free thyroxine (FT4) affects up to
10% of the adult population.Subclinical hypothyroidism may be categorized
as grade 1 when...
Diabetes
Care: Diabetes Journal: July, 2023Dietary sugars are associated with
various health issues, including overweight, obesity, cardiovascular diseases
(CVDs), and type 2 diabetes (T2D). Manufacturers have proposed
alternatives to reduce added sugars, notably by substituting artificial
sweeteners (e.g., aspartame, acesulfame potassium [K],...
Diabetes Care: May, 2023Type 2 diabetes is associated with
increased risk of microvascular and macrovascular disease, with the risk of
cardiovascular (CV) mortality more than double in people with type 2 diabetes
compared with those without. In the last decade, large dedicated
CV outcome trials in people with type 2 diabetes and at high risk or...
Diabetes Research and Clinical Practice: November
21, 2022The relationship between serum uric
acid levels and incident type 2 diabetes remains controversial.This cohort study assessed the
association between serum uric acid levels and the incidence of type 2 diabetes
in a Japanese population. TAKE-HOME MESSAGEThere was no significant
associati...
ADA: Diabetes Journals: Published June 2023Diabetes mellitus (DM) is one of the most important causes of
CKD. Moreover, both DM and CKD are important risk factors for cardiovascular
disease (CVD). Metformin is still the first-line drug for DM management. The
concern, of course, is an increased risk of metformin-associated lactic
acidosis (MALA)...
Thyroid disease can be broadly
categorised as thyroid dysfunction (hypothyroidism, hyperthyroidism) and
structural disease (goitre, nodules and cancer). Management is often
straightforward, but there are pitfalls that may lead to misdiagnosis,
overdiagnosis and inappropriate treatment. This article reviews the approach to
common thyroid proble...
