Comparative Efficacy and Tolerability of Luliconazole versus Terbinafin in Dermatophytosis of Pediatric Patients

Superficial fungal infections are primarily caused by dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the world’s population.

The lesion of dermatophytosis is present with an annular or ring-shaped red scaly plaque with central clearing, often associated with severe pruritus.

Systemic or topical antifungal drugs are used as treatment strategies to deal with fungal infections.

TAKE HOME MESSAGE

Luliconazole is a newer imidazole antifungal drug effective against a variety of fungal infections, especially dermatophytosis, which is one of the most common superficial fungal infections, caused by dermatophytes.

The present study is designed to compare the efficacy and tolerability of topical antifungal drug luliconazole with terbinafine used for the treatment of a variety of fungal infections, especially dermatophytosis.

In the present study, Authors found that the overall symptoms cure rate (composite score) of luliconazole was 99.6% while terbinafine had 89.73% composite score.

Conclusion:

In the present study Authors found that the luliconazole was more efficacious and tolerable than terbinafine at a short term therapy.

Also Luliconazole was better efficacious and tolerable than terbinafine in relieving signs and symptoms of dermatophytosis, especially pruritus and desquamation.

Read In Details


https://www.semanticscholar.org/paper/Comparative-Efficacy-and-Tolerability-of-versus-in-Kumar-Kumar/9745b96770dce592c883599f83a2397d22592996
https://ijcrr.com/uploads/4131_pdf.pdf

This is for informational purposes only. You should consult your clinical textbook for advising your patients.