Superficial fungal infections are primarily caused by
dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the
world’s population.
The lesion of dermatophytosis is present with an annular or
ring-shaped red scaly plaque with central clearing, often associated with
severe pruritus.
Systemic or topical antifungal drugs are used as treatment
strategies to deal with fungal infections.
TAKE HOME MESSAGE
Luliconazole is a newer imidazole antifungal drug effective
against a variety of fungal infections, especially dermatophytosis, which is
one of the most common superficial fungal infections, caused by dermatophytes.
The present study is designed to compare the efficacy and
tolerability of topical antifungal drug luliconazole with terbinafine used for
the treatment of a variety of fungal infections, especially dermatophytosis.
In the present study, Authors found that the overall symptoms
cure rate (composite score) of luliconazole was 99.6% while terbinafine had 89.73%
composite score.
Conclusion:
In the present study Authors found that the luliconazole was
more efficacious and tolerable than terbinafine at a short term therapy.
Also Luliconazole was better efficacious and tolerable than terbinafine in relieving signs and symptoms of dermatophytosis, especially pruritus and desquamation.
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