Human MetaPneumoVirus (hMPV) infection: what we need to know about this virus

A surge in cases of the flu-like human metapneumovirus (HMPV) in China has raised fears of another Covid-style pandemic.

Human metapneumovirus (HMPV) is a respiratory disease that causes flu or cold-like symptoms, but can increase risks or lead to more serious complications like bronchitis or pneumonia, particularly among the elderly, young children, and immunocompromised people.

The disease is in the same family as respiratory syncytial virus (RSV), and has been around since at least 2001 when it was first identified in the Netherlands. Its outbreaks are concentrated during colder seasons.

It is a seasonal disease that usually occurs in the winter and early spring, similar to RSV and the flu. Fears of a Covid-style pandemic are overblown, experts say the risk of another Covid-like pandemic is low.

The disease is already globally present and has been around for decades. This means people across the world have "some degree of existing immunity due to previous exposure".

HMPV is most likely spread from an infected person to others through

  • secretions from coughing and sneezing
  • close personal contact, such as touching or shaking hands
  • touching objects or surfaces that have the viruses on them then touching the mouth, nose, or eyes

Who is at risk for hMPV infection?

Human metapneumovirus is a common cause of upper respiratory infections among infants and children under 5 years old.

While anyone can catch hMPV, infants, older adults, and those with health conditions like immunosuppression, chronic obstructive pulmonary disease (COPD) and asthma are at higher risk for severe illness.

Extra care should be taken to protect at-risk groups and health care workers from any respiratory infections.

Doctors Liked to Read More

Human metapneumovirus (hMPV) is one of the viruses that causes the common cold (upper respiratory infection). It usually makes people only mildly sick, but it can make some people very sick.

The virus belongs to the Pneumoviridae family of viruses, along with respiratory syncytial virus (RSV). 

Generally, people infected with hMPV will have cold or flu-like symptoms:

  • cough
  • fever
  • sore throat
  • runny or stuffy nose
  • body ache
  • headache.

It can make a few people quite sick, causing infection of the lung (pneumonia) or inflammation of the airways to the lungs (bronchiolitis, bronchitis).

Symptoms of more severe disease include wheezing, difficulty breathing, chest pain, dizziness, severe fatigue, dehydration, or a persistent fever that does not improve. If someone is experiencing any of these severe symptoms, they should seek medical advice.

A polymerase chain reaction (PCR) test is the most reliable way to diagnose hMPV, giving accurate results within a few hours.  

However, doctors may not suggest this test for people with cold or flu-like symptoms as there is no specific treatment for hMPV infection and in most cases, it causes mild disease.

As hMPV is a cold virus, people can treat their symptoms with over-the-counter medicines to treat pain, fever, stuffy nose and cough. Getting plenty of rest and staying hydrated also helps.

Currently, there is no approved antiviral medicine for hMPV. Most people feel better in a few days. If symptoms get worse, they should contact their health care provider. Those who are at higher risk should also consult their doctor, even if their symptoms are not too bad.

In a small number of cases, when people need to be hospitalized, doctors may give them extra oxygen to help them recover.

Preventing hMPV infection is similar to preventing other respiratory illnesses with actions such as:

  • wearing a mask in crowded or poorly ventilated spaces
  • improving ventilation where possible (such as by opening a window for air flow)
  • cleaning hands regularly and thoroughly, with either soap and water or an alcohol-based hand rub
  • avoiding touching eyes, nose or mouth without cleaning hands first.

 

Having a strong immune system can also help fend off infections. Eating a balanced diet, exercising regularly, and sleeping properly help with that.

When someone is sick, they can avoid making others sick by

  • staying at home if they feel ill
  • covering nose and mouth with a tissue or bent elbow when coughing or sneezing
  • wearing a mask when around other people
  • improving ventilation, especially in shared spaces
  • regularly cleaning hands and disinfecting frequently touched surfaces.

 

There is currently no vaccine licensed for use against hMPV, but research is ongoing.

Read In Details


https://www.who.int/news-room/questions-and-answers/item/human-metapneumovirus-(hmpv)-infection
https://www.cdc.gov/human-metapneumovirus/about/index.html
https://www.bbc.com/news/articles/c23vjg7v7k0o

This is for informational purposes only. You should consult your clinical textbook for advising your patients.