Drug-information

JAMA Dermatology: Published November, 2022Despite the widespread use of nutritional supplements and dietary interventions for treating hair loss, the safety and effectiveness of available products remain unclear.The aim of the study is to evaluate and compile the findings of all dietary and nutritional interventions for treatment of hair loss a...
Pityriasis versicolor (PV) also known as tinea versicolor, which is chronic and superficial fungal skin disease caused by Malassezia yeasts. A permanent cure may difficult to achieve and this may explain the long-term nature of the disease. Consequently, a preventive treatment regimen may help to prevent the recurrence of pityriasis versicolor....
Thyroid disease can be broadly categorised as thyroid dysfunction (hypothyroidism, hyperthyroidism) and structural disease (goitre, nodules and cancer). Management is often straightforward, but there are pitfalls that may lead to misdiagnosis, overdiagnosis and inappropriate treatment. This article reviews the approach to common thyroid proble...
Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone. Iodine deficiency remains the most common cause of hypothyroidism worldwide.The most common symptoms in adults are fatigue, lethargy, cold intolerance, weight gain, constipation, depression, change in voice, and dry skin, but clinical presentation can di...
The Journal of Urology:Clomipramine is a tricyclic antidepressant (TCA) that has been found effective at a daily dose of 25 mg or 50 mg for premature ejaculation (PE) in multiple studies. Additionally, TCAs can carry significant side effects such as dizziness, dry mouth, and constipation. As a result, on-demand treatment is greatly preferred, e...
Dengue is the most common mosquito-borne, viral disease in the world. Dengue virus is a single stranded positive polarity RNA virus, belongs to the family Flaviviridae. The Den-2 and Den-3 variants of dengue are active this year and of the two, Den-2 is more prominent, according to the Institute of Epidemiology, Disease Control and Researc...
The British Journal of DermatologyDermatophytic infections have undergone unprecedented changes in India in the recent past. Oral antifungal drugs are considered to have a high cure rate in tinea corporis, tinea cruris and tinea faciei.Clinical trials to find out the effectiveness of the four main oral antifungal drugs are lacking.Authors teste...
Superficial fungal infections are primarily caused by dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the world’s population.The lesion of dermatophytosis is present with an annular or ring-shaped red scaly plaque with central clearing, often associated with severe pruritus.Systemic or topical antifungal drugs are used as...
JAMA Internal Medicine: Published on May, 2023Diabetic kidney disease is the leading cause of chronic kidney disease and end-stage kidney failure in the vast majority of the world. TAKE-HOME MESSAGEThis randomized clinical trial evaluated the use of glucose-lowering medications on kidney outcomes. A total of 5047 patients with type 2 diabet...
JAMA Internal Medicine: Published on May, 2023Diabetic kidney disease is the leading cause of chronic kidney disease and end-stage kidney failure in the vast majority of the world. TAKE-HOME MESSAGEThis randomized clinical trial evaluated the use of glucose-lowering medications on kidney outcomes. A total of 5047 patients with type 2 diabet...
Clinicians should be more judicious in prescribing or recommending oral or topical antifungal therapy.Given the limited selection of antifungals, it is paramount to mitigate resistant cases. Mitigation proposals include:·              good skin hygiene,·    &nb...
International Journal of Research in Dermatology: Published on February, 2021Dermatophytic infections are the most prevalent fungal infections, which affect majority of the global population. Indian climate, especially the hot and humid conditions contribute majorly to dermatophytosis. Azoles are the most commonly used antifungal agents due  t...