Drug-information

GERD is associated with substantial reductions in subjective well-being, lower work productivity, and increased healthcare use. The GERD in the Asia Pacific Survey (GAPS) found that GERD had a negative impact on well-being for 94% of respondents in terms of stress (68% of respondents), restrictions to daily activities (50%), and reduced wor...
ADA Diabetes Care Journal: Metformin is the recommended first-line pharmacotherapy for patients with type 2 diabetes, but most patients will ultimately require additional therapies to maintain glycemic control. Maintaining intensive glucose control early in the disease process may lead to legacy benefits that persist beyond the per...
PubMed Central: Published: July, 2021 Urticaria is a frequent, mast cell–driven disease that presents with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic idiopathic urticaria (CIU) is a common skin condition characterized by the appearance of recurrent wheals and/or angioede...
PubMed Central: Published: July, 2021 Urticaria is a frequent, mast cell–driven disease that presents with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic idiopathic urticaria (CIU) is a common skin condition characterized by the appearance of recurrent wheals and/or angioede...
A Systematic Review and Meta-analysisGastroesophageal reflux disease (GERD) is a chronic digestive disorder resulting from the reflux of gastric contents into the esophagus that is often accompanied by troublesome symptoms of heartburn, acid regurgitation, or other extra-esophageal symptoms such as chest pain, chronic cough, hoarseness or glob...
The Journal of Laryngology & OtologyThyroidectomy is one of the most common interventions in general and endocrine surgery for patients with hyperthyroidism, goiter, thyroid nodules or thyroid cancer.Post-operative hypocalcaemia is a recognized complication of thyroid surgery. The most common cause of acute symptomatic hypocalcemia in hospitali...
TAKE-HOME MESSAGEAbout 80% of pregnant women suffer from gestational reflux disease. Most interventions are based on a “step-up” approach that begins with lifestyle modifications. If the symptoms persist despite lifestyle modification, a medical intervention can be considered. Antacids, alginates and sucralfate are the first-line t...
The American Journal of Gastroenterology Gastroesophageal reflux disease (GERD) continues to be among the most common diseases seen by gastroenterologists, surgeons, and primary care physicians. GERD is the condition in which the reflux of gastric contents into the esophagus results in symptoms and/or complications. GERD is defined b...
Clinical Gastroenterology and Hepatology TAKE-HOME MESSAGE This review presents best practice advice statements to help healthcare providers in the treatment of patients with gastroesophageal reflux disease (GERD). To optimize care and response, diagnostic testing should be personalized and management should be tailored to the ind...
From The Journal of Infectious Diseases and The British Medical Journal: Sepsis mortality has improved following advancements in early recognition and standardized management, including emphasis on early administration of appropriate antimicrobials. However, guidance regarding antimicrobial duration in sepsis is surprisingly limited....
Take Home Messages: Derangement in calcium homeostasis is common in nephrotic syndrome (NS). It is asuumed that low serum total calcium and vitamin D levels are due to loss of protein-bound calcium and vitamin D. But it is unclear if free calcium and free vitamin D levels are truly low. The guideline is lacking with regards to calci...
Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain. PPI over prescription imposes an economic cost and contri...