Drug-information

Amoxicillin/Clavulanic Acid for the Treatment of Odontogenic Infections: Comparing Efficacy and Tolerability versus Clindamycin
International Journal of Dentistry: Odontogenic infections are one of the most prevalent diseases worldwide and the principal reason for seeking dental care. Dental prescriptions account for nearly 7% to 11% of all common antibiotic prescriptions. The commonest emergency odontogenic infections are periapical abscess (25%), pericoron...
Association between Proton Pump Inhibitor use and risk of Cardiovascular Disease
The American Journal of Gastroenterology: Proton pump inhibitors (PPIs) are a class of effective medications used to treat various acid-related disorders. Their use in the clinical setting has increased rapidly and tremendously. PPIs are among the most commonly used medications worldwide. However, the widespread availability of these...
Short versus Long-Term Antibiotic Prophylaxis in Cesarean Section
Cesareans delivery is the most common risk factor for postpartum maternal infections, which occurs at a rate of 18%–38%. Factors that have been associated with an increased risk of infection among women who have a cesarean delivery include emergency cesarean section, labor and its duration, ruptured membranes and the duration of rupture, t...
Amoxicillin plus Clavulanic Acid VS Amoxicillin in the Treatment of Community Acquired Pneumonia in Children
Community-acquired pneumonia (CAP) is a significant cause of respiratory morbidity and mortality in children, especially in developing countries. Worldwide, CAP is the leading cause of death in children younger than five years. Clinical assessment requires careful evaluation of clinical features, severity, and evidence of complications....
Guidelines on the Management of Eosinophilic Oesophagitis in Children and Adults
The British Medical Journal (BMJ): British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelineThese joint consensus guidelines from the British adult and paediatric gastroenterology societies utilize the GRADE methodology to make recommendatio...
Guidelines on the Diagnosis of Eosinophilic Oesophagitis in Children and Adults
The British Medical Journal (BMJ): British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines Eosinophilic oesophagitis is a condition characterised by symptoms of dysphagia and/or food impaction in adults, and feeding problems, abdominal...
Vitamin and Mineral Supplementation for the Prevention of CVD and Cancer: An Updated Report from the USPSTF
JAMA: The Journal of the American Medical Association: Published June 21, 2022 Cardiovascular disease and cancer are the 2 leading causes of death. Vitamin and mineral supplementation has been proposed as a preventive strategy for both diseases because of shared disease pathways involving oxidative stress, inflammation, and methionine m...
The safety of Amoxicillin and Clavulanic acid use during the first trimester of Pregnancy
The British Pharmacological Society Journal: Published: 05 September 2019 Penicillin’s are widely used during pregnancy for various bacterial infectious indications. Amoxicillin, rapidly crosses the placenta following absorption to the bloodstream, It is prescribed both as a sole medicine as well as in combination with clavulanic acid mos...
The Effect of the COVID-19 Pandemic on Urine Culture Results and Resistance to Antibiotics
Urinary tract infections (UTIs) represent a common pathology among female patients, leading to overprescribing antibiotics, globally. The emergence of the COVID-19 pandemic has dramatically increased the incidence of this particular viral pneumonia with secondary bacterial superinfection, resulting in continuous therapeutic or prophylactic...
Antacid & Alginate is more effective than antacid in controlling post-prandial oesophageal acid exposure in GERD patients
Heartburn is a cardinal symptom of gastro-oesophageal reflux disease (GERD) and is among the most common patient complaints encountered by physicians. TAKE HOME MESSAGE: This study compared the effect of Antacid & Alginate Liquid to an antacid in controlling post-prandial acid reflux in GERD patients. The current investigation demons...
Amoxicillin-Clavulanic Acid Empirical Oral Therapy for Management of Children with Acute Haematogenous Osteomyelitis
PubMed Central: Published on 2020 August AHOM was defined as any bone infection with a period between symptoms onset and diagnosis < two weeks. AHOM was defined complicated in the presence of sepsis, septic shock, arthritis, cellulitis, sub-periosteal or muscle abscess, deep vein thrombosis pathological fracture, septic emboli or hosp...
Supplemental Calcium and Vitamin D for Cardiovascular Disease Prevention and Treatment
Journal of the American College of Cardiology (JACC): Published on Feb 2021 Calcium and Vitamin D supplements are commonly used, often together, to optimize bone health. Multiple observational studies have linked low serum 25-hydroxyvitamin D concentrations with increased cardiovascular risk. Given their widespread availability, lo...