Drug-information

Onychomycosis: Practical Approaches to Minimize Relapse and Recurrence
Journal of Drugs in DermatologyToenail onychomycosis is a common disease in which treatment options are limited and treatment failures and disease recurrence are frequently encountered. It usually requires many months of treatment and recurrence may occur in more than half of the patients within 1 year or more after the infection has been erad...
Tinea Capitis Asymptomatic Carriers: Evidence behind Treatment
Journal of the European Academy of Dermatology and Venereology (JEADV): Published on November, 2021Tinea capitis is a highly contagious scalp condition that is common in children 3-7 years of age but can be found in all ages. It can present with a spectrum ranging from scaly, patchy alopecia with or without "blackdots" to purulent inflammation...
Diagnosis and Treatment of Infertility in Men
JAMA: The Journal of the American Medical Association: Published on November, 2022American Urological Association (AUA) and American Society for Reproductive Medicine (ASRM) provide an overview of current guidelines on the evaluation and treatment of male infertility and is an important tool for providers caring for these patients.With up to 20...
Seborrhoeic dermatitis of the Scalp
PubMed Central: BMJ Clinical EvidenceSeborrhoeic dermatitis affects at least 3% to 10% of the population and causes red patches with greasy scales on the face, chest, skin flexures, and scalp.The cause of seborrhoeic dermatitis is unknown. Malassezia yeast species are thought to have an important role.The inflammatory process may be mediated i...
Expert Consensus on the Management of Dermatophytosis in India
BioMed Central (BMC Dermatol) Journal: ECTODERM IndiaSuperficial fungal infections are caused by dermatophytes, non-dermatophytic moulds and commensal yeasts. Dermatophytes, the most common causative agents, are assuming high significance in developing countries like India.Currently, dermatologists across India are inundated with cases of derm...
Helicobacter pylori Eradication for Primary Prevention of Aspirin-Associated Peptic Ulcer Bleeding
The Lancet: Published on November, 2022Aspirin is widely recommended for the secondary prevention of thrombotic vascular disease.  Its use is limited principally by increased risk of bleeding, particularly from the gastrointestinal tract.The risks of upper gastrointestinal bleeding can be mitigated in part by acid suppression with proton pump i...
Efficacy of Terbinafine and Itraconazole in Different Doses and in Combination in the Treatment of Tinea Infection
Indian Journal of Dermatology: Published on July, 2020A Randomized Controlled Parallel Group Open Labeled Trial with Clinico-Mycological Correlation.Tinea is a superficial fungal infection caused by dermatophytes which invade and multiply within the keratinized tissue (skin, hair, nails). Approximately 20%-25% of the world population is affecte...
Head and Neck Dermatitis, A Subtype of Atopic Dermatitis: Treatment outcomes in adolescent and adult patients
Pediatric Dermatology: Published on November 2020Head and neck dermatitis (HND) is a clinical variant of atopic dermatitis (AD), presenting in adolescence or adulthood and characterized by involvement of the head, neck, and superior part of the trunk. The role of Malassezia spp has been advocated in the pathogenesis of HND, and antifungal agent...
Outcomes in Children of Women with Type 2 Diabetes Exposed to Metformin vs Placebo during Pregnancy
The Lancet Diabetes & Endocrinology: Published on February, 2023Metformin is increasingly being used during pregnancy, with potentially adverse long-term effects on children. This study aimed to examine adiposity in children of women with type 2 diabetes from the Metformin in Women with Type 2 Diabetes in Pregnancy (MiTy) trial, with and withou...
Duration of Antibiotic Treatment for Gram-Negative Bacteremia
eClinicalMedicine Journal: The LANCET: Published on December, 2022Gram-negative bacteremia is common in both community and health care settings, with a significant increase in incidence described for some Gram-negative bacteria in recent years.Prolonged duration of antibiotic therapy for such common infections may lead to increased resistance em...
Chlorthalidone vs Hydrochlorothiazide for Hypertension-Related Cardiovascular Events
The New England Journal of Medicine: Published on December, 2022Hypertension increases the risk of complications and death from cardiovascular disease. Thiazide diuretics are first-line antihypertensive agents that lower blood pressure and prevent adverse cardiovascular outcomes. Early studies suggested that chlorthalidone was superior to hydro...
Idiopathic pulmonary fibrosis and gastroesophageal reflux disease (GERD)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibroinflammatory lung disease associated with increased morbidity and mortality. As its name suggests, the exact cause of the disease is not known. However, some genetic and environmental factors have been observed concurrently with the condition and are considered potential etiolo...