Drug-information
Journal of Fungi: A Systematic
Review of Randomized Controlled Trials
Tinea pedis, or athlete’s foot, is
a superficial fungal infection of the skin of the feet caused by dermatophytes,
most commonly Trichophyton rubrum, Trichophyton mentagrophyte and
Epidermophyton floccosum.
Tinea pedis is common worldwide,
with more than 70% of t...
The majority (70-93%) of adolescents have discomfort associated
with menstruation. Dysmenorrhea is the most common reason for missed school and
activities. Up to 20-40% report missed school due to dysmenorrhea, and 40%
report a negative effect on school performance and concentration. Adolescents
with severe dysmenorrhea have impaired qualit...
Endometriosis
affects up to 10% of women of reproductive age, and the main goal of treatment
is to relieve symptoms. Progestins have been the mainstay of endometriosis
suppression, of which dienogest has become an important option in many parts of
the world.
A
search of PubMed was conducted for papers published between 2007–2019 o...
Pretreatment with Dienogest in women with Endometriosis undergoing IVF after a previous failed cycle
Endometriosis
is a benign chronic inflammatory estrogen-dependent disease and a well-known cause
of infertility. Endometriosis may have a direct harmful effect on fertility not
only due to the presence of adhesions and anatomic distortions, but also
because of the intrinsic negative impact on oocyte development, embryogenesis,
or implantat...
Acute
upper gastrointestinal bleeding (AUGIB) is a common medical emergency. In
Western countries, its incidence was estimated to be over 100 cases per 100 000
adults per year. Fortunately, the mortality rates of AUGIB have decreased over
the past few decades, largely attributable to improvements in endoscopic and
pharmacological therapies...
Gastroesophageal reflux disease
(GERD) and idiopathic pulmonary fibrosis (IPF) are two pathological conditions
often strictly related, even if a clear relationship of causality has not been
demonstrated.
GERD is a frequent comorbidity in
IPF patients, as demonstrated using combined multichannel intraluminal
impedance-pH, despite being...
Alimentary Pharmacology & Therapeutics:
Functional dyspepsia is
characterised by troublesome early satiety, fullness, or epigastric pain or
burning. It can easily be overlooked as the symptoms overlap with
gastro-oesophageal reflux disease and irritable bowel syndrome.
It affects 10% of the population
and is more prevalent in women....
Proton Pump Inhibitors (PPIs) are widely considered the
mainstay of medical treatment for GERD. Multiple publications have raised questions about adverse
events, raising doubts about the safety of long-term use and increasing concern
about overprescribing of PPIs. This guideline provides updated, evidence-based recommendations and
practical...
Indian Journal of Gastroenterology: Published:
30 June 2022
TAKE HOME MESSAGE:
Nocturnal acid breakthrough (NAB)
may differ based on duration of proton pump inhibitor (PPI) action and Helicobacter
pylori (H. pylori) infection; NAB may influence esophageal
acidification (EA) and mucosal damage.
Dexlansoprazole, a long-acting PPI,...
PubMed Central: Published on October 2019
Status epilepticus is most common
in children younger than 5 years, with incidence between 10 and 60 per 100,000
populations.
Convulsive status for 30 min leads
to irreversible neuronal injury.
TAKE HOME MESSAGE
Established Status Epilepticus
Treatment Trial proposed that 35%–45% of p...
Efficacy of Montelukast in preventing seasonal recurrence of vernal keratoconjunctivitis in Children
TAKE-HOME MESSAGEVernal keratoconjunctivitis is a
chronic, seasonally exacerbated, allergic inflammation of the eye.This prospective study evaluated
the efficacy and safety of montelukast in conjunction with typical topical
therapies for treating pediatric vernal keratoconjunctivitis (VKC). Patients
were evaluated for subjective improvement in...
Hypertension is one of the leading
public health challenges worldwide. It is common in both developed and
developing countries.
Essential hypertension is believed
to be a result of complex interaction of genetic and environmental factors.
Increased peripheral resistance is responsible for most of the cases of
essential hypertension....
