Drug-information
JAMA Cardiology: Published on April, 2022TAKE-HOME MESSAGEQuestion: Is
low-dose triple combination antihypertensive therapy associated with greater
time at target blood pressure compared with usual care?Findings: This
secondary analysis of an open-label randomized controlled clinical trial
evaluated whether low-dose triple combination antihyp...
Asthma, a highly prevalent chronic
inflammatory disease of the airways, is characterized by a variable degree of
airflow obstruction, edema, and bronchial hyper responsiveness caused by
chronic exposition to allergens or associated to other diseases such as gastro
esophageal reflux. The complex genetic actions and
environmental triggers intric...
Clinical Diabetes and Endocrinology Journal: Published: May 2022Diabetes Mellitus (DM) is a debilitating metabolic disorder
characterized by impaired insulin function, leading to chronic hyperglycemia.Diabetic nephropathy (DN) is one of the most common and
severe microvascular complications of DM, occurring in about 20–30% of diabetic
patients,...
The LANCET: Diabetes &
Endocrinology: Published on July, 2022Diabetes is a major cause of death,
cardiovascular complications, and health-care burden worldwide.People with type 2 diabetes who
have high blood pressure are at an increased risk of morbidity and death from
major cardiovascular events.However, there are inadequate
randomised contro...
Seizures are the most common
manifestation of neurological insult during the neonatal period. The most common
cause of symptomatic neonatal seizures is hypoxic/ischemic encephalopathy (HIE)
which affects approximately 1-2/100 live births.There are no evidence-based
guidelines for the pharmacologic treatment of neonatal seizures and management...
Diabetes, Obesity and Metabolism Journal:
PubMedTAKE HOME MESSAGE:The study aims to investigate the
effect of sequential treatment escalation with empagliflozin and linagliptin on
laboratory markers of α- and β-cell function in people with type 2 diabetes
mellitus (T2DM) insufficiently controlled on metformin monotherapy.The researchers found t...
Hand-foot-and-mouth disease (HFMD)
is a common but highly contagious acute viral infection due to an enterovirus infection. The disease is most common under the age of 10, and most are under 5
years of age (95%). It can uncommonly affect adults and tends to be more severe
in the elderly, immunocompromised, and pregnant women. What is the cause...
Conjunctivitis
is one of the most common causes of red-eye and affects patients of all ages
and socioeconomic class. Viral conjunctivitis is responsible for the majority
of infectious conjunctivitis, accounting for up to 75% of cases and is more
prevalent in the summer.What
is conjunctivitis?Conjunctivitis,
also known as "pink eye", is inflam...
Dengue
is endemic in Bangladesh with recurrent outbreaks. Health officials in
Bangladesh have reported elevated dengue fever activity in Bangladesh during
2022. Dhaka and Chattogram has become a hotspot for dengue fever (DF).Why DF rising in August &
September?•
The risk of
dengue fever transmission in Bangladesh exists nationwide and...
The 2021 WHO hypertension guideline
aims to provide the most current and relevant evidence based global public
health guidance on the initiation of treatment (with pharmacological agents)
for hypertension in adults. The recommendations target adult,
non-pregnant patients who were appropriately diagnosed with hypertension and counseled
about li...
AHA Journals: Hypertension: Published on May, 2022Diabetes is a strong risk factor
for end-stage renal disease (ESRD). Hypertension also plays a crucial role
in the development and progression of kidney failure. Blood pressure (BP)
rises with declining kidney function which in turn aggravates hypertension. Moreover, as chronic kidney disease
(C...
Gliomas are the most common malignant primary brain tumors
and treatment options are multimodal. Seizures are a well-recognized
symptom in glioma patients and occur frequently, either as a presenting symptom
or during the course of the disease. The incidence of seizures is higher
in slow-growing tumors.Seizure control plays an important role in...
