Drug-information

AHA Journal: Circulation: Published on February, 2023Low-density lipoprotein cholesterol (LDL-C) level is a well-established risk factor for atherosclerotic cardiovascular disease. However, the optimal achieved LDL-C level with regard to efficacy and safety in the long term remains unknown.TAKE-HOME MESSAGEThis study assessed the relationship...
AHA Journal: Stroke: A Journal of Cerebral Circulation: Published on June, 2022Millions of women worldwide use exogenous hormones as oral contraceptives or hormone replacement therapy. Still, time-dependent and long-term consequences of exogenous hormones on stroke risk remains unclear.TAKE-HOME MESSAGEIn this UK Biobank analysis including 257,...
Nature Reviews: Urology: Published on August, 2022Premature ejaculation (PE) is a prevalent and common male sexual dysfunction. The first treatment modalities for PE were with psychotherapy focussing on the sexual relationship and anxiety related to sexual satisfaction with a partner. The use of sexual psychology can play a role in the...
The American Journal of Gastroenterology GERD MEDICAL MANAGEMENT Management of GERD requires a multifaceted approach, taking into account the symptom presentation, endoscopic findings, and likely physiological abnormalities. Medical management includes lifestyle modifications and pharmacologic therapy, principally with medication...
Malaria is a life-threatening disease caused by Plasmodium parasites, which are spread to humans through bites of infected mosquitoes.The World Health Organization (WHO) is recommended on October 2021, widespread use of the RTS,S/AS01 (RTS,S) malaria vaccine among children in sub-Saharan Africa and in other regions with moderate to high P. falc...
Diabetes Research and Clinical Practice: Published on July, 2022The American Diabetes Association recommends that metformin should be started at the time of type 2 diabetes mellitus (T2DM) diagnosis, unless there are contraindications. Metformin is safe, effective, economic, and might reduce the risk of cardiovascular events and death. When gl...
American Heart Association Journal: Published on February, 2021TAKE HOME MESSAGE:What Is New?To determine the impact of differences in blood pressure between arms on cardiovascular outcomes (eg, heart attack, death), data from over 57 000 individuals from 24 studies around the world were collated into one large dataset and analyzed.Results sugge...
Stroke: A Journal of Cerebral Circulation: Published on April, 2022High blood pressure (BP) is common after ischemic stroke and associated with a poor functional outcome and increased mortality. Reducing blood pressure (BP) is a highly effective strategy for long-term stroke prevention. Despite overwhelmingly clear evidence from randomized tri...
Hypertension is the most common non-communicable disease, which persists as a major risk factor of cardiovascular diseases such as stroke, myocardial Infarction, and heart failure. Another major problem in clinical practice was the patients' adherence to treatment, directly related to the number of hypertension pills to be taken.Thus, determini...
Journal of Hypertension: Most patients with hypertension require more than one drug to attain recommended blood pressure (BP) targets. Initiating therapy with two agents is recommended for patients at high risk of a cardiovascular event. Fixed drug combinations are increasingly used in antihypertensive therapy, so it is necessary to...
Clinical trials in hypertension have repeatedly shown that adequate blood pressure (BP) control is important for the prevention of cardiovascular morbidity and mortality. However, most patients do not achieve target BP levels, and the majority of them require combination therapy with two or more drugs in order to obtain an adequate BP redu...
American Family Physician (AFP) Journal: Seborrheic dermatitis is a common skin condition in infants, adolescents, and adults. Seborrheic dermatitis is a chronic inflammatory dermatologic condition that usually appears on areas of the body with a large density of sebaceous glands, such as the scalp, face, chest, back, axilla, and gro...