Drug-information

International Journal of Clinical Obstetrics and Gynecology: Published 2021Abnormal uterine bleeding is defined as any type of bleeding that is abnormal in volume, frequency, duration and periodicity. Frequent complaints include heavy and prolonged menstrual bleeding with or without pain, passage of clots, fatigue and lethargy. AUB is...
TAKE HOME MESSAGERequests for thyroid tests are increasing, although in many cases clinical need is not evident.If thyroid dysfunction is suspected, measuring TSH alone is recommended as the first step. Test T4 only when TSH is abnormal.Ultrasound should be considered for patients with thyroid dysfunction and goitre (enlarged thyroid) or palp...
PubMed Central: November, 2022Tinea versicolor is a common superficial fungal infection of the skin with various clinical manifestations. This review aims to familiarize physicians with the clinical features, diagnosis and management of tinea versicolor.Tinea versicolor is caused by Malassezia species, notably M. globosa, M....
Infection and Drug Resistance Journal:Tinea is superficial fungal infections typically caused by dermatophytes.Superficial fungal infections are widespread, with an estimated worldwide prevalence of 20%–25%, and include tinea pedis (athlete’s foot), tinea cruris (jock itch), and tinea corporis (ringworm), among othersTopical allylamine (terbinaf...
Indian Journal of Pharmacology: Published: May, 2019Dermatophytic infections are the common fungal infections aggravated by hot and humid climate. Terbinafine and Itraconazole are commonly used oral antifungal agents for the same. However, resistance to these drugs is being seen increasingly when used in the conventional doses and duration. In...
JAMA: The Journal of the American Medical Association: July, 2019Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine (FT4) affects up to 10% of the adult population.Subclinical hypothyroidism may be categorized as grade 1 when...
Clinical Neurophysiology: April 2023Long term symptoms following COVID-19 (Long COVID) now affects a large number of patients with estimates of up to 100 million people world-wide.Prolonged “long-COVID” (P-L–COVID), seen several months after even a mild COVID-19 infection, is characterized by a complexity of neuromuscular, musculoskeletal, and...
Clinical Gastroenterology and Hepatology: February, 2022The incidence rate of hepatocellular carcinoma (HCC) has been increasing for the last 3 decades. Fatty liver progresses from fat accumulation to inflammation to fibrosis to cirrhosis to cancer. Recent evidence suggests potential clinical benefits of statin in cancer chemoprevention a...
Principles of TherapyTopical AntifungalsTopical medications have better pharmacokinetics than their systemic counterparts. Hence, the combination is expected to have better mycological clearance than systemic and topical alone. The combination should be from different groups for wide coverage and also to prevent the emergence of resistance. Dru...
International Journal of Scientific Study (IJSS): May, 2020Superficial fungal infections are caused by dermatophytes, non-dermatophytic molds, and commensal yeasts. According to published literature, the global prevalence rate of superficial mycotic infection has been found to be 20–25%. The recent prevalence of dermatophytosis in India ranges f...
Diabetes Care: May, 2023Type 2 diabetes is associated with increased risk of microvascular and macrovascular disease, with the risk of cardiovascular (CV) mortality more than double in people with type 2 diabetes compared with those without. In the last decade, large dedicated CV outcome trials in people with type 2 diabetes and at high risk or...
American Journal of Ophthalmology: Published May, 2023Glaucoma is a disease characterized by progressive deterioration of the optic nerve and retinal nerve fiber layer (RNFL) defect with corresponding visual field changes.Globally, both the prevalence of chronic kidney disease (CKD) and glaucoma are rising rapidly. These 2 diseases share a comm...