Gastrointestinal-hepatic-disorders

Reflux esophagitis is an esophageal mucosal injury that occurs secondary to retrograde flux of gastric contents into the esophagus. Clinically, this is referred to as gastroesophageal reflux disease (GERD).Fig: EsophagitisWhich PPI is Superior?Some of the present study demonstrated that Esomeprazole gave faster symptom relief in patients with R...
Published in JAMA: The Journal of the American Medical AssociationThis full article is available on the publisher's site-https://jamanetwork.com/journals/jama/fullarticle/2768929Expert comment By David Rakel MD, FAAFP Esther Millard Endowed Professor, University of Wisconsin School of Medicine & Public Health; Chair, Department of Family Medicin...
The study was conducted in Bangladesh among malnourished children and highly appreciated among world experts. Full article has been published in The New England Journal of Medicine.https://www.nejm.org/doi/full/10.1056/nejmoa2023294One Expert Comment: Written by David Rakel MD, FAAFP  Nutrition Is Mor...
GERD is a chronic disorder of the digestive system caused by the lower esophageal sphincter not closing properly. This can allow gastric acid, bile into esophagus, causing inflammation and, in some cases, tooth erosion.GERD occurs more commonly in individuals who are:Overweight or obese because of increased pressure on the abdomen.Pregnant...
A Double Action Antacid & Alginate Liquid was more effective than an antacid in controlling postprandial esophageal acid exposure in GERD patients. This suggests that this main effectiveness related to its co-localization with and displacement/neutralization of the post-prandial acid pocket, rather than preventing reflux.Heartburn is...
Esomeprazole Dose - 20mg/40mg WHEN, HOW and WHY?Esomeprazole is a proton pump inhibitor used to -·        treat GERD, ·        reduce the risk of NSAID associated gastric ulcers, ·        eradicate H. pylori, and · ...
Many reflux patients remain symptomatic on a standard dose of proton pump inhibitor (PPI). In some patients, especially those with nonerosive reflux disease or atypical GERD symptoms, acid-suppressive therapy with PPIs is not as successful. In patients with residual reflux symptoms despite PPI treatment, adding an alginate plus antacid offe...
Comparative study of PPI for symptom relief in patients with reflux esophagitis: Some of the present study demonstrated that esomeprazole gave faster symptom relief than pantoprazole, lansoprazole and omeprazole. Because: Esomeprazole has been shown to have a faster onset of anti-secretory...