Gastrointestinal-hepatic-disorders
Gastroesophageal reflux disease
(GERD) and idiopathic pulmonary fibrosis (IPF) are two pathological conditions
often strictly related, even if a clear relationship of causality has not been
demonstrated.
GERD is a frequent comorbidity in
IPF patients, as demonstrated using combined multichannel intraluminal
impedance-pH, despite being...
Alimentary Pharmacology & Therapeutics:
Functional dyspepsia is
characterised by troublesome early satiety, fullness, or epigastric pain or
burning. It can easily be overlooked as the symptoms overlap with
gastro-oesophageal reflux disease and irritable bowel syndrome.
It affects 10% of the population
and is more prevalent in women....
Proton Pump Inhibitors (PPIs) are widely considered the
mainstay of medical treatment for GERD. Multiple publications have raised questions about adverse
events, raising doubts about the safety of long-term use and increasing concern
about overprescribing of PPIs. This guideline provides updated, evidence-based recommendations and
practical...
Indian Journal of Gastroenterology: Published:
30 June 2022
TAKE HOME MESSAGE:
Nocturnal acid breakthrough (NAB)
may differ based on duration of proton pump inhibitor (PPI) action and Helicobacter
pylori (H. pylori) infection; NAB may influence esophageal
acidification (EA) and mucosal damage.
Dexlansoprazole, a long-acting PPI,...
GERD is associated with substantial
reductions in subjective well-being, lower work productivity, and increased
healthcare use. The GERD in the Asia Pacific Survey (GAPS) found that GERD had
a negative impact on well-being for 94% of respondents in terms of stress (68%
of respondents), restrictions to daily activities (50%), and reduced wor...
A Systematic Review and
Meta-analysisGastroesophageal reflux disease (GERD) is a chronic digestive
disorder resulting from the reflux of gastric contents into the esophagus that
is often accompanied by troublesome symptoms of heartburn, acid regurgitation,
or other extra-esophageal symptoms such as chest pain, chronic cough,
hoarseness or glob...
American College of Gastroenterology (ACG 2021): Sequencing of
Stool Samples technology eliminates need for endoscopic gastric biopsyHelicobacter
pylori is a major human pathogen for which increasing antibiotic
resistance constitutes a serious threat to human health. Antimicrobial
resistance is an ever-growing problem for successful eradication...
TAKE-HOME MESSAGEAbout 80%
of pregnant women suffer from gestational reflux disease. Most
interventions are based on a “step-up” approach that begins with lifestyle
modifications. If the
symptoms persist despite lifestyle modification, a medical intervention can be
considered.
Antacids,
alginates and sucralfate are the first-line t...
The American Journal of
Gastroenterology
Gastroesophageal
reflux disease (GERD) continues to be among the most common diseases seen by
gastroenterologists, surgeons, and primary care physicians.
GERD is
the condition in which the reflux of gastric contents into the esophagus
results in symptoms and/or complications. GERD is defined b...
Clinical Gastroenterology and Hepatology
TAKE-HOME MESSAGE
This review presents best practice
advice statements to help healthcare providers in the treatment of patients
with gastroesophageal reflux disease (GERD).
To optimize care and response,
diagnostic testing should be personalized and management should be tailored to
the ind...
Proton
pump inhibitors (PPIs) are among the most commonly used medications in the
world. Developed for the treatment and prevention of acid-mediated upper
gastrointestinal conditions, these agents are being used increasingly for
indications where their benefits are less certain.
PPI over prescription
imposes an economic cost and contri...
BMJ Open Diabetes Research & Care: BMJ Journal
Bangladeshi researchers identify
new pathological cause of diabetes.
The team
of researchers from multiple local and foreign universities, through a
five-year (2015-2020) study on 574 non-diabetic people aged between 30 and 60,
have discovered that deficiency of the Intestinal Alkaline Ph...
