Antacid & Alginate effectively relief Heartburn than Antacid

A Double Action Antacid & Alginate Liquid was more effective than an antacid in controlling postprandial esophageal acid exposure in GERD patients.

This suggests that this main effectiveness related to its co-localization with and displacement/neutralization of the post-prandial acid pocket, rather than preventing reflux.

Heartburn is a cardinal symptom of gastro-esophageal reflux disease (GERD) and is among the most common patient complaints.

Antacids neutralize gastric acid in a short timeframe after ingestion but the effect is soon overcome by meal-stimulated acid secretion. Alternatively, an alginate-antacid combination creates a ‘raft’ floating on top of the ingested chyme that co-localizes in the region of the acid pocket, potentially offering more effective targeted therapy.

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What are the Uses

Treatment of symptoms resulting from the reflux of acid, bile and pepsin into the oesophagus such as acid regurgitation, heartburn and indigestion, for example following meals or during pregnancy, and for symptoms of hyperacidity.

Can also be used to treat the symptoms of gastro-oesophageal reflux during concomitant treatment with or following withdrawal of acid suppressing therapy.

Currently, antacid use is restricted to the relief of mild intermittent gastroesophageal reflux disease (GERD) associated heartburn.

Special warnings and precautions for use:

This product is considered high in sodium. This should be particularly taken into account for those on a low salt diet (e.g. in some cases of congestive heart failure and renal impairment).

Each 20 ml contains 260 mg (6.5 mmol) of calcium. Care needs to be taken in treating patients with hypercalcaemia, nephrocalcinosis and recurrent calcium containing renal calculi.