Gastrointestinal-hepatic-disorders
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The authors of this meta-analysis evaluated the
efficacy of alginate-containing compounds for the treatment of
gastroesophageal reflux disease (GERD) symptoms. The odds of resolution of
GERD symptoms was significantly greater with alginate-based therapies than
with placebo or antacids. Alginate therap...
The management of gastroesophageal
reflux disease (GERD) has been revolutionized with the development of proton
pump inhibitors (PPIs). Unfortunately, due to the inherent pharmacokinetic and
pharmacodynamic profiles of conventional PPIs, many patients continue to suffer
from symptoms related to GERD despite appropriate use of PPIs.
Curr...
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The
authors investigated physician adherence with recommending peptic ulcer
disease (PUD) prophylaxis for elderly patients who were receiving dual
antiplatelet therapy or anticoagulation or who were at risk of bleeding
PUD, as per expert consensus guidelines from the American College of
Gastroenterol...
Eosinophilic esophagitis (EoE) is a
chronic immune-mediated inflammatory disease of the esophagus. Symptoms of EoE includes
vomiting, dysphagia, or feeding difficulties. Genetic factors and environmental
factors, such as exposure to antibiotics early in life, are associated with
EoE.TAKE-HOME MESSAGE
EoE affects approximately 34.4/100,000 peo...
Peptic ulcer disease is often defined as a mucosal break
greater than 3-5 mm in the stomach or duodenum with a visible depth. It is
therefore an endoscopic diagnosis in contrast to dyspepsia, which is a clinical
diagnosis based on symptoms alone. Peptic ulcer disease results from an
imbalance between factors that protect the mucosa of the stoma...
Antacids neutralize gastric acid
and are, broadly used in the
treatment of gastroesophageal reflux disease (GERD) in adults. They are
utilized for more than 2,000 years, though evidence of the effectiveness and
safety is limited in infants [1]. Antacids have an effect on the short-term
relief of heartburn and the healing of esophagitis. Charac...
Gastrointestinal (GI) bleeding is
the most common GI diagnosis necessitating. Upper GI bleeding (UGIB) refers to
bleeding originating from sites in the esophagus, stomach, or duodenum.AbstractThe American Journal of
Gastroenterology society performed systematic reviews addressing predefined
clinical questions to develop recommendations with the...
The American Journal of GastroenterologyTAKE-HOME MESSAGE
In a study evaluating sleep position and nocturnal
gastroesophageal reflux, the sleep positions of 57 individuals referred
for ambulatory pH impedance were measured and analyzed. The left lateral
position was associated with significantly shorter acid exposure time than...
Dyspepsia is defined as having one
or more symptoms of epigastric pain, burning, postprandial fullness, or early
satiation. Bloating and nausea often coexist
with dyspepsia but are nonspecific and are thus not included in its definition.
Heartburn is also excluded from diagnostic symptom criteria for dyspepsia since
it is thought to primarily...
Reflux disease is a chronic and
progressive condition. Treatment options depend on the disease stage. The
disease stage is determined by the severity of reflux into the esophagus. This
in turns depends on how frequent and how long are the reflux episodes. GERD is also associated with a
spectrum of symptoms that ranges from mild heartburn to sev...
Many women experience heartburn
during pregnancy. It can be extremely uncomfortable and can negatively affect
women’s experience of pregnancy and their quality of life.Dietary changes may help to
reduce or stop heartburn. The NICE guideline on gastrooesophageal reflux
disease and dyspepsia in adults includes recommendations about dietary and
l...
A Peptic ulcer is a small sore or
lesion in the lining of stomach or duodenum, the first part of the intestine.
This sore is often aggravated by stomach acid, but is usually not caused by the
acid itself. More likely, the cause is either a bacterium known as Helicobacter
pylori (H. pylori) or taking non-steroidal
anti-inflammatory drugs (NSAID...
