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From the operating rooms, pulse
oximetry spread to the recovery room, then the ICUs. Now its use is widespread
throughout the hospital. By reducing the incidence of unrecognized hypoxia,
pulse oximetry has reduced inpatient mortality immeasurably. Pulse oximeter a
valuable tool, but has limitations too.
The AstraZeneca-Oxford vaccine is
a recombinant adenoviral vector vaccine. Recombinant vaccines use a small piece
of genetic material from a pathogen, like SARS-CoV-2, to trigger an immune
response. A specific piece of the virus can be targeted, and recombinant
vaccines are generally safe to use in a large population of people—even those
with...
The ChAdOx1 nCoV-19 vaccine was
developed by the University of Oxford and AstraZeneca and manufactured in Serum
Institute of India.
The vaccine works by delivering
the genetic code of the SARS-CoV-2 spike protein to the body’s cells, similarly
to the BNT162b2 vaccine. Once inside the body, the spike protein is produced,
causing the immune...
What do we know about this new
SARS-CoV-2 variant?
It’s been snappily named
VUI-202012/01 (the first “Variant Under Investigation” in December 2020) and is
defined by a set of 17 changes or mutations. One of the most significant is an
N501Y mutation in the spike protein that the virus uses to bind to the human
ACE2 receptor. Changes in this...
In a clinical trial of patients with COVID-19, monoclonal antibody were shown to reduce COVID-19-related
hospitalization or emergency room visits in patients at high risk for
disease progression within 28 days after treatment when compared to
placebo. The safety and effectiveness of this investigational therapy
for use in the treatment of C...
FDA Authorizes Monoclonal Antibody for Treatment of COVID-19. The U.S. FDA issued an emergency use authorization (EUA)
for the investigational monoclonal antibody therapy for
the treatment of mild-to-moderate COVID-19 in adult and pediatric
patients.
The World Health Organization has
granted its first emergency use validation to BioNTech-Pfizer's COVID-19
vaccine.
UN health agency says emergency use
listing ‘opens the door’ for countries to expedite their vaccine approval
processes.
The World Health Organization has
listed Pfizer-BioNTech’s COVID-19 vaccine for emergency use, a crit...
The U.S. Food and Drug
Administration issued an emergency use authorization (EUA) for the second vaccine
— this one developed by Moderna for the prevention of coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2).
Authorized Use
For the prevention of 2019
coronavir...
Pfizer and BioNTech Announce Vaccine Candidate Against COVID-19 Achieved Success in First Interim Analysis from Phase 3 StudyVaccine
candidate was found to be more than 90% effective in preventing
COVID-19 in participants without evidence of prior SARS-CoV-2 infection
in the first interim efficacy analysisAnalysis evaluated 94 confirmed cases...
National guidelines on clinical management of Coronavirus disease by Disease Control Division, Directorate General of Health Services, Ministry of Health & Family Welfare & Government of the People's Republic of Bangladesh.The guideline includes clinical management of COVID-19 and is updated with the latest evidence and the WHO guidelines.
Why is herd immunity
important?
Herd immunity occurs when a large
portion of a community (the herd) becomes immune to a disease, making the
spread of disease from person to person unlikely. As a result, the whole
community becomes protected — not just those who are immune.
Often, a percentage of the
population mus...
