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What is already known about this topic? Face masks or respirators (N95/KN95s) effectively filter virus-sized particles in laboratory settings. The real-world effectiveness of face coverings to prevent acquisition of SARS-CoV-2 infection has not been widely studied. What is added by this report? Consistent use of a face mask or res...
Clinical Infectious Diseases: By Infectious Diseases Society of America TAKE-HOME MESSAGE This study addressed the predictors of SARS-CoV-2 infection among participants who reported social contact with an individual known or suspected of having SARS-CoV-2 infection. Among unvaccinated and partially vaccinated participants, factors suc...
JAMA Internal Medicine: Key Points Question What is the risk of perinatal complications associated with SARS-CoV-2 infection during pregnancy and what factors are associated with hospitalizations? Findings In this cohort study of 43 886 pregnant individuals, SARS-CoV-2 infection during pregnancy was associated with an increased ris...
BMJ: British Medical Journal This retrospective case series analysis compared the incidence of immune-mediated neurologic events among over 8 million individuals vaccinated against COVID-19, over 700,000 unvaccinated individuals diagnosed with COVID-19, and a historical cohort of over 14 million individuals in the general population....
European Journal of Neurology: Neurological complications associated with acute coronavirus disease 2019 (COVID-19) are well described. Now, increasing evidence suggests that symptoms may persist even beyond 4–12 weeks after disease onset Frequent neurological, cognitive and neuropsychiatric long-term symptoms after COVID-19 include b...
American Journal of Obstetrics and Gynecology: Key findings Vaccine-generated antibodies were present in umbilical cord blood and breastmilk after maternal vaccination. Pregnant and lactating women elicited comparable vaccine-induced humoral immune responses with nonpregnant controls and generated higher antibody titers than those o...
JAMA Network: SARS-CoV-2 continues to infect more than 22 million patients per week and globally causes more than 65 000 deaths per week as of January 31, 2022. Although aspirin has not been shown to reduce major adverse cardiovascular or pulmonary events in symptomatic outpatients with COVID-19, several observational studies have fou...
American College of Physicians (ACP) Journals: Annals of Internal Medicine Nirmatrelvir–ritonavir (NMV/r) is use in high-risk patients with mild to moderate COVID-19 who are likely to be receiving other medications. NMV/r administered within three days of symptom onset reduced the risk of COVID-19 related hospitalization and death from a...
European Heart Journal: Emerging as a new epidemic, long COVID or post-acute sequelae of coronavirus disease 2019 (COVID-19), a condition characterized by the persistence of COVID-19 symptoms beyond 3 months. The long-term impact of COVID-19 on cardiovascular (CV) health and mortality is also emerging as a major global concern. Definit...
The human pancreas is a target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). New-onset hyperglycaemia and insulin resistance have been reported in patients with coronavirus disease-2019 (Covid-19) without history of diabetes. However, it is unclear whether such metabolic alterations are transient or whether individu...
The FDA has authorized use of the nirmatrelvir/ritonavir, for the treatment of mild to moderate COVID-19. Studies have indicated that it is 88% effective at preventing hospitalization and death from COVID-19. Criteria for Prescribing To prescribe nirmatrelvir/ritonavir, prescribers should confirm that the following criteria have been...
Urinary tract infections (UTIs) represent a common pathology among female patients, leading to overprescribing antibiotics, globally. The emergence of the COVID-19 pandemic has dramatically increased the incidence of this particular viral pneumonia with secondary bacterial superinfection, resulting in continuous therapeutic or prophylactic...