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The U.S. Food and Drug
Administration (USFDA) issued an emergency use authorization (EUA) for a new
monoclonal antibody for the treatment of COVID-19 that retains activity against
the omicron variant.
The EUA for Bebtelovimab is for the treatment of mild to moderate COVID-19 in
adults and pediatric patients (12 years of age and older we...
The COVID-19 Treatment Guidelines:
On December 22 and 23, 2021, the
Food and Drug Administration (FDA) issued Emergency Use Authorizations (EUAs)
that allow 2 new oral antiviral agents to be used in this patient population:
ritonavir-boosted nirmatrelvir and molnupiravir.
Ritonavir-Boosted Nirmatrelvir
Nirmatrelvir is an orally bi...
The American Journal of
Gastroenterology
Gastroesophageal
reflux disease (GERD) continues to be among the most common diseases seen by
gastroenterologists, surgeons, and primary care physicians.
GERD is
the condition in which the reflux of gastric contents into the esophagus
results in symptoms and/or complications. GERD is defined b...
From The Journal of Infectious Diseases and
The British Medical Journal:
Sepsis mortality has improved
following advancements in early recognition and standardized management, including
emphasis on early administration of appropriate antimicrobials. However,
guidance regarding antimicrobial duration in sepsis is surprisingly limited....
Proton
pump inhibitors (PPIs) are among the most commonly used medications in the
world. Developed for the treatment and prevention of acid-mediated upper
gastrointestinal conditions, these agents are being used increasingly for
indications where their benefits are less certain.
PPI over prescription
imposes an economic cost and contri...
JAMA Surgery:
Surgical
site infections (SSIs) are infections of the incision or organ or space that
occur after surgery. Surgical patients initially seen with more
complex comorbidities and the emergence of antimicrobial-resistant pathogens
increase the cost and challenge of treating SSIs. The prevention of SSI is
increasingly important...
The British Medical Journal (BMJ):
British Society of
Gastroenterology (BSG) and British Society of Paediatric Gastroenterology,
Hepatology and Nutrition (BSPGHAN) joint consensus guidelineThese joint consensus guidelines
from the British adult and paediatric gastroenterology societies utilize the
GRADE methodology to make recommendatio...
The British Medical Journal (BMJ):
British Society of Gastroenterology (BSG) and British
Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN)
joint consensus guidelines
Eosinophilic oesophagitis is a condition characterised by
symptoms of dysphagia and/or food impaction in adults, and feeding problems,
abdominal...
European Heart Journal: Published: 10 July 2022
Adding salt to foods (usually at
the table) is a common eating behavior directly related to an individual's
long-term preference to salty taste foods and habitual salt intake. Indeed, in
western diet, adding salt at the table accounts for 6–20% of total salt intake.
In addition, the com...
American Epilepsy Society issues
guideline and treatment algorithm for convulsive status epilepticus. The
guideline was endorsed by the Epilepsy Foundation, Child Neurology Society, and
American College of Emergency Physicians.Status epilepticus – continuous or rapid sequential seizure activity for
30 minutes or more – is a medical emergency wi...
Hormone therapy is the most
effective treatment for vasomotor symptoms (VMS) and other menopausal symptoms.
Changing estrogen levels during menopause may impact multiple components
involved in maintaining temperature homeostasis.Health care professionals should
individualize therapy based on clinical factors and patient preference. They
should...
A Report
of the American Academy of Neurology (AAN) Guideline Subcommittee:Levodopa preferred as initial dopaminergic therapy for motor symptoms in
patients with early Parkinson disease.Parkinson
disease (PD) is a neurodegenerative disorder that causes both motor and
nonmotor symptoms and increases in prevalence with age. Motor symptoms in the...
