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In this UK Biobank study, the
authors sought to evaluate the correlation between serum testosterone levels
and cardiac events, finding no association between total testosterone and risk
for major adverse cardiovascular events (MACE).
Men with lower total testosterone
concentrations wer...
Paracetamol has often been cited as
a safer alternative to non-steroidal anti-inflammatory drugs (NSAIDs) with
regards blood pressure and cardiovascular health. But now researchers have
raised concerns about this, suggesting that those taking paracetamol long-term
may be at greater risk of heart attack and stroke.Long-term paracetamol use could...
Gastrointestinal (GI) bleeding is
the most common GI diagnosis necessitating. Upper GI bleeding (UGIB) refers to
bleeding originating from sites in the esophagus, stomach, or duodenum.AbstractThe American Journal of
Gastroenterology society performed systematic reviews addressing predefined
clinical questions to develop recommendations with the...
COVID-19 Update:In light of the most recent
information and data available, today, the FDA revised the authorizations for
two monoclonal antibody treatments – bamlanivimab
and etesevimab (administered together) and casirivimab and imdevimab – to limit their use to only when the
patient is likely to have been infected with or exposed to a varian...
Restless legs syndrome (RLS) is a
condition characterized by discomfort at rest and urge to move focused on the
legs. RLS may occur as an idiopathic, often hereditary condition (primary RLS),
or in association with medical conditions (secondary RLS) including iron
deficiency, uremia, and polyneuropathy. Current understanding of the
pathophysio...
The U.S. Centers for Disease
Control and Prevention announced that the recommended isolation time for
people with COVID-19 is now reduced from
10 to 5 days for those who are asymptomatic.
The agency said that people who test
positive should isolate for 5 (five) days, and if they are asymptomatic, or
their symptoms are resolving (without fe...
This clinical practice guideline
for the evaluation and diagnosis of chest pain provides recommendations and
algorithms for clinicians to assess and diagnose chest pain in adult patients.The “2021
AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of
Chest Pain” provides recommendations based on contemporary evidence on...
Physical Examination
Causes of chest pain are numerous; the initial evaluation
should focus on those that are life-threatening, such as ACS, PE, aortic
dissection, and esophageal rupture, to facilitate rapid implementation of
appropriate treatment. Specific clues can be helpful. Chest tenderness on
palpation or pain with inspiration markedly...
Diabetes, a silent killer, is a
leading cause of neuropathy. Around 50% of diabetic patients develop peripheral
neuropathy in 25 years. Painful diabetic neuropathy manifests as burning,
excruciating, stabbing or intractable type of pain or presents with tingling or
numbness. The pathophysiology of this
condition is due to primarily metabolic a...
The American Academy of
Pediatrics (AAP) and the American Academy of Family Practice
(AAFP) published updated guidelines for the diagnosis and medical
management of AOM. Otitis media (OM) is any inflammation
of the middle ear. Otitis media is among the most common issues faced by
physicians caring for children. Approximately 80% of children w...
This is a summary of the American
Academy of Neurology (AAN) and Child Neurology Society (CNS) evidence-based
guideline reviewing all available evidence on the assessment of the child with
status epilepticus (SE). Status epilepticus (SE) is a
medical condition characterized by repeated epileptic seizures without complete
recovery between seizu...
Insulin Initiation in Patients
with Type 2 Diabetes
Insulin initiation and titration is
a challenge for many primary care providers (PCPs) involved in the treatment of
patients with type 2 diabetes. What are ADA recommendations?The early introduction of insulin should be considered -· if
there is evidence of ongoing catabolism (weight...
