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AGA Gastroenterology Journal: Published on November, 2022In adults, obesity-related complications, such as cardiovascular disease, stroke, type 2 diabetes mellitus (T2DM), nonalcoholic steatohepatitis, obstructive sleep apnea, osteoarthritis, and certain types of cancer (eg, colorectal cancer), have also increased, contributing to high morbidit...
The American Journal of Gastroenterology GERD MEDICAL MANAGEMENT Management of GERD requires a multifaceted approach, taking into account the symptom presentation, endoscopic findings, and likely physiological abnormalities. Medical management includes lifestyle modifications and pharmacologic therapy, principally with medication...
Gastroesophageal reflux disease (GERD) continues to be among the most common diseases seen by gastroenterologists, surgeons, and primary care physicians. The American College of Gastroenterology (ACG) recently released an updated guideline on diagnosis and management of GERD which was published by the American Journal of Gastroenterology. In t...
Pathogenesis of adenomyosis involves sex steroid hormone abnormalities, inflammation, fibrosis and neuro angiogenesis, even though the proposed mechanisms are not fully understood. Nowadays, adenomyosis may also be diagnosed by non-invasive techniques, because of imaging advancements.     Adenomyosis often coexists with other gynecologic...
NICE guidelines:Take Home MessagesDo not offer an antibiotic for preventing or treating Pneumonia if SARS-CoV-2, another virus, or a fungal infection is likely to be the cause.Evidence as of March 2021 suggests that bacterial co-infection occurs in less than about 8% of people with COVID-19, and could be as low as 0.1% in people in hospital wit...
The National Institute for Health and Care Excellence (NICE) GuidanceManaging cough Recommendations·       Encourage patient with cough to avoid lying on their backs, if possible, because this may make coughing less effective.·       Be aware that older people or those with comorbidities, frailty, impaired immunity or a reduced ability to cough...
NICE guidelines:Antibiotic treatment in the communityRecommendationsDo not offer an antibiotic for preventing secondary bacterial pneumonia in people with COVID 19. If a person has suspected or confirmed secondary bacterial pneumonia, start antibiotic treatment as soon as possible. Advise people to seek medical help without delay if their sympt...
The U.S. Food and Drug Administration (USFDA) issued an emergency use authorization (EUA) for a new monoclonal antibody for the treatment of COVID-19 that retains activity against the omicron variant. The EUA for Bebtelovimab is for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age and older we...
The COVID-19 Treatment Guidelines: On December 22 and 23, 2021, the Food and Drug Administration (FDA) issued Emergency Use Authorizations (EUAs) that allow 2 new oral antiviral agents to be used in this patient population: ritonavir-boosted nirmatrelvir and molnupiravir. Ritonavir-Boosted Nirmatrelvir Nirmatrelvir is an orally bi...
The American Journal of Gastroenterology Gastroesophageal reflux disease (GERD) continues to be among the most common diseases seen by gastroenterologists, surgeons, and primary care physicians. GERD is the condition in which the reflux of gastric contents into the esophagus results in symptoms and/or complications. GERD is defined b...
From The Journal of Infectious Diseases and The British Medical Journal: Sepsis mortality has improved following advancements in early recognition and standardized management, including emphasis on early administration of appropriate antimicrobials. However, guidance regarding antimicrobial duration in sepsis is surprisingly limited....
Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain. PPI over prescription imposes an economic cost and contri...