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JAMA Internal Medicine: Published on May, 2023Diabetic kidney disease is the leading cause of chronic
kidney disease and end-stage kidney failure in the vast majority of the
world. TAKE-HOME MESSAGEThis randomized clinical trial evaluated the use of
glucose-lowering medications on kidney outcomes. A total of 5047 patients with type 2 diabet...
American Journal of Ophthalmology: Published on December, 2022In this study, the analysis of
characteristics of patients with diabetes and Diabetic Retinopathy (DR) and
their association with the development of Alzheimer's disease (AD) and dementia
revealed.TAKE-HOME MESSAGEThe presence of Diabetic Retinopathy
(DR) for >5 years was significantl...
The Lancet Diabetes & Endocrinology: Published on
February, 2023Metformin is increasingly being
used during pregnancy, with potentially adverse long-term effects on children. This study aimed to examine
adiposity in children of women with type 2 diabetes from the Metformin in Women
with Type 2 Diabetes in Pregnancy (MiTy) trial, with and withou...
Effect of SGLT2 Inhibitors on Kidney and CV Events in Patients with Advanced Diabetic Kidney Disease
Diabetes Research and Clinical Practice: Published
on December,
2022Sodium-Glucose Transport Protein 2
(SGLT2) Inhibitors also called gliflozins are a class of medicine used to lower
high blood glucose levels in people with type 2 diabetes. Medicines in the
SGLT2 inhibitor class include Canagliflozin, Dapagliflozin, Empagliflozin, Ertugli...
Clinical Diabetes and Endocrinology Journal: Published: May 2022Diabetes Mellitus (DM) is a debilitating metabolic disorder
characterized by impaired insulin function, leading to chronic hyperglycemia.Diabetic nephropathy (DN) is one of the most common and
severe microvascular complications of DM, occurring in about 20–30% of diabetic
patients,...
The LANCET: Diabetes &
Endocrinology: Published on July, 2022Diabetes is a major cause of death,
cardiovascular complications, and health-care burden worldwide.People with type 2 diabetes who
have high blood pressure are at an increased risk of morbidity and death from
major cardiovascular events.However, there are inadequate
randomised contro...
Diabetes, Obesity and Metabolism Journal:
PubMedTAKE HOME MESSAGE:The study aims to investigate the
effect of sequential treatment escalation with empagliflozin and linagliptin on
laboratory markers of α- and β-cell function in people with type 2 diabetes
mellitus (T2DM) insufficiently controlled on metformin monotherapy.The researchers found t...
AHA Journals: Hypertension: Published on May, 2022Diabetes is a strong risk factor
for end-stage renal disease (ESRD). Hypertension also plays a crucial role
in the development and progression of kidney failure. Blood pressure (BP)
rises with declining kidney function which in turn aggravates hypertension. Moreover, as chronic kidney disease
(C...
FDA News Release: Published on November, 2022Type one diabetes mellitus (T1DM)
is an autoimmune disease characterized by gradual destruction of beta cells in
islets of Langerhans. Teplizumab is a humanized anti- CD3 monoclonal antibody,
which have beneficial effects for T1DM patients.The U.S. Food and Drug
Administration (FDA) has approved tepl...
Coronavirus disease 2019 (COVID-19)
is one of the most significant pandemics in human history caused by the virus
known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
SARS-CoV-2 has infected >530 million people, of which >6.3 million have
died since June 23, 2022. Recent research has indicated that
COVID-19 might be a risk fa...
Diabetes Care: Published on December 2022With the numbers of people with
type 2 diabetes rising worldwide, dietary modifications provide an essential
therapeutic approach for blood glucose, weight, and cardiovascular risk-factor
management. Intermittent fasting (IF) has
emerged as an alternative to classic daily caloric reduction. The approache...
ACP Journals: Annals of Internal Medicine: Published
on February 2023In this systematic review and
meta-analysis, the authors assessed whether vitamin D administration decreases
the risk for diabetes in individuals with prediabetes. TAKE-HOME MESSAGECombining data from three
randomized trials, the authors demonstrated that vitamin D reduced the...
