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Diabetes, Obesity & Metabolism Journal: Published on November, 2022TAKE-HOME MESSAGEThis open-label randomized trial assessed the safety and efficacy of oral insulin (Capsulin) in patients with poorly controlled type 2 diabetes on metformin alone. Participants on the 150-IU and 300-IU dose of oral insulin saw a significant decrease in HbA1c lev...
Diabetes Care Journal: Published on January 2023Gestational diabetes (GDM) is a complex disorder associated with adverse fetal and maternal outcomes. GDM is a global problem and has an estimated prevalence of 14%. The term gestational glucose intolerance (GGI) is applied to women who have an abnormal screening 50-g glucose challenge test (...
Diabetes Research and Clinical Practice: Published on July, 2022The American Diabetes Association recommends that metformin should be started at the time of type 2 diabetes mellitus (T2DM) diagnosis, unless there are contraindications. Metformin is safe, effective, economic, and might reduce the risk of cardiovascular events and death. When gl...
ADA Diabetes Care Journal: Metformin is the recommended first-line pharmacotherapy for patients with type 2 diabetes, but most patients will ultimately require additional therapies to maintain glycemic control. Maintaining intensive glucose control early in the disease process may lead to legacy benefits that persist beyond the per...
BMJ Open Diabetes Research & Care: BMJ Journal Bangladeshi researchers identify new pathological cause of diabetes. The team of researchers from multiple local and foreign universities, through a five-year (2015-2020) study on 574 non-diabetic people aged between 30 and 60, have discovered that deficiency of the Intestinal Alkaline Ph...
Diabetes Journal: ADA publications Several randomized clinical trials have shown the possibility of preventing or delaying the onset of type 2 diabetes in nondiabetic adults at high risk of developing the disease. Successful interventions have included drugs (not further discussed here) and lifestyle interventions emphasizing weight loss...
In patients with type 2 diabetes mellitus, insulin may be used to augment therapy with oral glycemic medications or as insulin replacement therapy.The goals of therapy should be individualized based on many factors, including age, life expectancy, comorbid conditions, duration of diabetes, risk of hypoglycemia, cost, patient motivation, and qu...
The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Recommendations Chronic Kidney Disease - Screening At...
JAMA Internal MedicineTAKE-HOME MESSAGEThis retrospective study evaluated the association between statin initiation and diabetes progression. Progression of diabetes occurred in significantly more statin users. There was a dose–response relationship with higher-intensity statin use.The study examined 12 years of data on patients covered by the...
Treatment guidelines for type 2 diabetes mellitus (T2DM) recommend initiating pharmacotherapy with an oral antidiabetic drug (OAD) to reduce hyperglycaemia when diet and exercise are inadequate. International guidelines recommend metformin as the first OAD, whereas Japanese guidelines recognize that other OADs may be more appropriate i...
Diabetes Care: American Diabetes Association Journal The standard pharmacotherapy for management of type 2 diabetes mellitus (T2DM) involves initiation with monotherapy (usually metformin) unless there are contraindications or intolerance, followed by sequential addition of other single agents, when target glycaemic control is not achieved o...
Children who are infected with COVID-19 are at a higher risk of developing diabetes, according to a new study by the Centers for Disease Control and Prevention (CDC). Increased incidence of diabetes seen among patients aged younger than 18 years after acute COVID-19 infection versus those without COVID-19. Key Summary What is already...