Covid-19

An Aid to the Management of COVID-19 in Bangladesh: “Lessons from the western experience” New 5th Edition This book is a small effort by some highly-motivated Bangladeshi doctors living in the UK and the USA to supplement local guidelines in Bangladesh. This will hopefully enable local experts in Bangladesh to be kept updated...
Pfizer and BioNTech Announce Vaccine Candidate Against COVID-19 Achieved Success in First Interim Analysis from Phase 3 StudyVaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysisAnalysis evaluated 94 confirmed cases...
Bangladesh has entered into a deal with the Serum Institute of India (SII) to acquire 30 million doses of a potential vaccine being developed by AstraZeneca for Covid-19.SII and Bangladesh’s drugmaker Beximco Pharma signed a Memorandum of Understanding (MoU) for priority delivery of the vaccine doses.Under the deal, Beximco will purchase five milli...
Remdesivir, Hydroxychloroquine, Lopinavir and Interferon regimens appeared to have little or no effect on hospitalized COVID-19, as indicated by overall mortality, initiation of ventilation and duration of hospital stay. The mortality findings contain most of the randomized evidence on Remdesivir and Interferon, and are consistent with me...
In a paper on the interim findings on the four drugs, WHO's Solidarity trial researchers in 30 countries return a clear negative. The multi-country Solidarity trial anchored by the World Health Organization (WHO) has concluded that none of the four repurposed drugs that it examined — remdesivir, hydroxychloroquine (HCQ),...
National guidelines on clinical management of Coronavirus disease by Disease Control Division, Directorate General of Health Services, Ministry of Health & Family Welfare & Government of the People's Republic of Bangladesh.The guideline includes clinical management of COVID-19 and is updated with the latest evidence and the WHO guidelines.
Details Background: The Gamaleya Research Institute in Russia is testing their non-replicating viral vector COVID-19 vaccine candidate, Sputnik V (formerly Gam-COVID-Vac), in two Phase 1/2 trials. The trials recruited about 38 participants each to receive the vaccine candidate (NCT04436471) (NCT04437875).   Outcomes...
Pharmaceutical company AstraZeneca and Oxford University have resumed clinical trials of their COVID-19 vaccine candidate in the United Kingdom after a brief global pause in testing. AstraZeneca put a hold on its COVID-19 clinical trials worldwide this week while it investigated an adverse reaction in...
Oxford researchers halt vaccine trial while adverse reaction is investigated One of the leading covid-19 vaccine candidate trials has been voluntarily paused as part of a standard review process triggered by a “single event of an unexplained illness that occurred in the UK phase III trial.” The...
Why is herd immunity important? Herd immunity occurs when a large portion of a community (the herd) becomes immune to a disease, making the spread of disease from person to person unlikely. As a result, the whole community becomes protected — not just those who are immune. Often, a percentage of the population mus...
Beximco Pharmaceuticals, one of the leading drug makers of the country, announced today it will invest with Serum Institute of India (SII) to ensure Bangladesh receives Covid-19 vaccine on a priority basis, once approved by the regulator. In a press statement, Beximco Pharmaceuticals said it will make a financial contribution...
Remdesivir The broad-spectrum antiviral agent remdesivir is a nucleotide analog prodrug. On May 1, 2020, The FDA has granted an emergency use authorization (EUA) for remdesivir to treat hospitalized adults and children with suspected or laboratory-confirmed SARS CoV-2 infection and severe COVID-19 disease.   MANDATORY REQUIREMENTS FOR R...