Take-home-message
Cracked heels, or heel fissures, are caused by dry, thickened
skin around the heels, often resulting in discomfort, pain, and potential
complications like infections or cellulitis.Common in elderly individuals, diabetics, and those with
prolonged weight-bearing activities, contributing factors include dry skin,
improper footwear, medical condit...
The British Journal of Dermatology: Published: 16
September 2024Retinoids, widely used in
dermatology for treating acne and various skin conditions, have raised concerns
regarding potential side effects, particularly sexual dysfunction. Although
retinoids are effective in managing skin conditions, their association with sexual
dysfunction is b...
Archives of Dermatological Research: Published: August 2024Vitiligo, an autoimmune condition characterized by
depigmented skin patches due to the loss of functional melanocytes, has been
linked to dysregulation in the JAK-STAT signaling pathway, particularly in
IFN-g signaling. The use of JAK inhibitors, such as ruxolitinib cream, a JAK1
and JA...
Pharmacologic Approaches to
Glycemic Treatment:
The goals
in caring for patients with diabetes mellitus are to eliminate symptoms and to
prevent, or at least slow, the development of complications. FIND BELOW TREATMENT RECOMMENDATIONS FOR TYPE 2 DIABETES:
Management of hypertensionMany guidelines exist for the management of hypertension.
Most groups, including the JNC, the American Diabetes Associate (ADA), and the
American Heart Association/American Stroke Association (AHA/ASA) recommend
lifestyle modification as the first step in managing hypertension.Lifestyle modificationsJNC 7 recommendation...
APPROACH CONSIDERATIONS
The goal of treatment is to provide
adequate relief of pain. At a minimum, pain relief should be sufficient to
allow women to perform most, if not all, of their usual activities and to
reduce the productivity loss commonly associated with dysmenorrhea.
Treatment of primary dysmenorrhea
can be initiated empiric...
Journal of Diabetes and its Complications: September
2023Kidney disease is a diabetes-related
complication and diabetes is the most common cause of end-stage kidney disease
(ESKD) in the world.This study analyzed the incidence of kidney disease in the
Diabetes Prevention Program Outcomes Study.TAKE-HOME MESSAGEAfter 21
years of randomization i...
Annals of Internal Medicine: Published May 2024Testosterone (T) levels slowly
decline as we age, and serum hormone-binding globulin (SHBG) levels gradually
increase. As SHBG increases, there is less T available to the tissues. There
are several conditions that reduce levels of T; these include being overweight,
having metabolic dysfunction, liv...
Gastroenterology: AGA Journal: Published March, 2019Prior research has shown an
association between proton pump inhibitors and fracture risk. This study
checked for markers for bone reabsorption and formation and followed bone
mineral density and the incidence of fractures. It also looked at levels of
calcium, magnesium, phosphorous, and parath...
Neurogastroenterology and Motility Journal: Published:
September 2022GERD is a condition that develops
when the reflux of stomach contents causes troublesome symptoms and/or
complications. These symptoms include typical ones, such as heartburn,
regurgitation, or both, angina-mimicking non-cardiac chest pain, and
extra-esophageal symptoms,...
Clinical, Cosmetic and Investigational Dermatology: Published
on December 2022Seborrheic dermatitis (SD) is a
common chronic inflammatory skin disorder that most commonly affects young
adults, and less often children. In adolescents and adults, SD clinical
presentation may range from a mild scalp scaling to diffuse white, yellowish
patches in...
Artificial intelligence-powered
medical technologies are rapidly evolving into applicable solutions for
clinical practice. Deep learning algorithms can deal with increasing amounts of
data provided by wearables, smartphones, and other mobile monitoring sensors in
different areas of medicine. AI has revolutionized medical
technologies and can b...
