Take-home-message

Archives of Dermatological Research: Published: August 2024Vitiligo, an autoimmune condition characterized by depigmented skin patches due to the loss of functional melanocytes, has been linked to dysregulation in the JAK-STAT signaling pathway, particularly in IFN-g signaling. The use of JAK inhibitors, such as ruxolitinib cream, a JAK1 and JA...
Pharmacologic Approaches to Glycemic Treatment: The goals in caring for patients with diabetes mellitus are to eliminate symptoms and to prevent, or at least slow, the development of complications. FIND BELOW TREATMENT RECOMMENDATIONS FOR TYPE 2 DIABETES:
Management of hypertensionMany guidelines exist for the management of hypertension. Most groups, including the JNC, the American Diabetes Associate (ADA), and the American Heart Association/American Stroke Association (AHA/ASA) recommend lifestyle modification as the first step in managing hypertension.Lifestyle modificationsJNC 7 recommendation...
APPROACH CONSIDERATIONS The goal of treatment is to provide adequate relief of pain. At a minimum, pain relief should be sufficient to allow women to perform most, if not all, of their usual activities and to reduce the productivity loss commonly associated with dysmenorrhea. Treatment of primary dysmenorrhea can be initiated empiric...
Journal of Diabetes and its Complications: September 2023Kidney disease is a diabetes-related complication and diabetes is the most common cause of end-stage kidney disease (ESKD) in the world.This study analyzed the incidence of kidney disease in the Diabetes Prevention Program Outcomes Study.TAKE-HOME MESSAGEAfter 21 years of randomization i...
Annals of Internal Medicine: Published May 2024Testosterone (T) levels slowly decline as we age, and serum hormone-binding globulin (SHBG) levels gradually increase. As SHBG increases, there is less T available to the tissues. There are several conditions that reduce levels of T; these include being overweight, having metabolic dysfunction, liv...
Gastroenterology: AGA Journal: Published March, 2019Prior research has shown an association between proton pump inhibitors and fracture risk. This study checked for markers for bone reabsorption and formation and followed bone mineral density and the incidence of fractures. It also looked at levels of calcium, magnesium, phosphorous, and parath...
Neurogastroenterology and Motility Journal: Published: September 2022GERD is a condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications. These symptoms include typical ones, such as heartburn, regurgitation, or both, angina-mimicking non-cardiac chest pain, and extra-esophageal symptoms,...
Clinical, Cosmetic and Investigational Dermatology: Published on December 2022Seborrheic dermatitis (SD) is a common chronic inflammatory skin disorder that most commonly affects young adults, and less often children. In adolescents and adults, SD clinical presentation may range from a mild scalp scaling to diffuse white, yellowish patches in...
Artificial intelligence-powered medical technologies are rapidly evolving into applicable solutions for clinical practice. Deep learning algorithms can deal with increasing amounts of data provided by wearables, smartphones, and other mobile monitoring sensors in different areas of medicine. AI has revolutionized medical technologies and can b...
The Lancet Diabetes & Endocrinology: Published December, 2023Inflammation has been implicated in the pathogenesis of diabetes. This study investigated the randomised treatment effect of low-dose aspirin on incident type 2 diabetes and fasting plasma glucose (FPG) concentrations among older adults.TAKE-HOME MESSAGEThis post hoc analysis of...
Artificial intelligence (AI) can be defined as the branch of computer science dealing with the simulation of intelligent human behavior in computers. It is done by creating algorithms that can solve problems and are programmed for all the specificities of the problem. Dermatology has taken the leading position for the implementation of AI in t...