Take-home-message

JAMA Internal Medicine: Published on May, 2023Diabetic kidney disease is the leading cause of chronic kidney disease and end-stage kidney failure in the vast majority of the world. TAKE-HOME MESSAGEThis randomized clinical trial evaluated the use of glucose-lowering medications on kidney outcomes. A total of 5047 patients with type 2 diabet...
PubMed: Published on April 2022Seborrheic dermatitis (SD) is a common inflammatory skin disease, which is particularly prevalent in older adults, presenting with papulosquamous morphology in areas rich in sebaceous glands, particularly the scalp, face, and body folds.PathogenesisWhile a specific cause of seborrheic dermatitis remains largely un...
AHA Journals (Circulation): Published on November, 2022Once patients have completed their dual antiplatelet therapy, we need to stop one of the medications — which one — ASA or clopidogrel? For many of us, we will keep the ASA and get rid of the other agent like clopidogrel.This study in Korea included 5438 patients who had PCI with drug-elutin...
Onychomycosis is accounting for up to 50% all nail disorders. It causes not only physical but also psychosocial and emotional distress to the patient. Treatment of the disease is far from satisfactory mainly due to high cost and long duration of therapy with poor patient compliance.TAKE HOME MESSAGE:This study aims to compare the efficacy of pu...
AACE Endocrine Practice Journal: Published on May, 2022Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease affecting 25% of the global population. NAFLD is associated with cardiometabolic disorders: (1) obesity, (2) insulin resistance, (3) type 2 diabetes mellitus, (4) high blood pressure, and (5) at...
Indian Journal of Dermatology, Venereology, and Leprology: Published on 2019A 28-year-old man, undergoing treatment for vitiligo, presented with complaints of new lesions on the neck for the last 1 week. On examination, multiple hypopigmented macules were seen on the neck.Figure 1: Patient with vitiligo (red arrow) showing multiple hypopigment...
The Lancet Diabetes & Endocrinology: Published on February, 2023Metformin is increasingly being used during pregnancy, with potentially adverse long-term effects on children. This study aimed to examine adiposity in children of women with type 2 diabetes from the Metformin in Women with Type 2 Diabetes in Pregnancy (MiTy) trial, with and withou...
The Lancet: Published on January, 2023The appropriate duration of postoperative antibiotics for complex appendicitis is unclear. The increasing global threat of antimicrobial resistance warrants restrictive antibiotic use, which could also reduce side-effects, length of hospital stay, and costs.TAKE-HOME MESSAGEThis pragmatic, open-label, rando...
AHA Journal: Stroke: A Journal of Cerebral Circulation: Published on June, 2022Millions of women worldwide use exogenous hormones as oral contraceptives or hormone replacement therapy. Still, time-dependent and long-term consequences of exogenous hormones on stroke risk remains unclear.TAKE-HOME MESSAGEIn this UK Biobank analysis including 257,...
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The LANCET: Published on December, 2022Oral antivirals have been an important addition to efforts to minimise adverse COVID-19 outcomes in individuals at high risk.The earlier first trial of molnupiravir showed only a 30% reduction of hospitalisations and deaths with molnupiravir compared with placebo. Subsequent observational studies in...
JAMA Network: Published on April, 2022CVD remains a leading cause of morbidity and mortality globally. Prevention strategies must address all aspects of a patient’s lifestyle habits, including healthy nutrition, physical activity, smoking cessation, and stress reduction. When an individual’s risk is sufficiently high, pharmacologic therapy is o...