Take-home-message

AHA Journals (Circulation): Published on November, 2022Once patients have completed their dual antiplatelet therapy, we need to stop one of the medications — which one — ASA or clopidogrel? For many of us, we will keep the ASA and get rid of the other agent like clopidogrel.This study in Korea included 5438 patients who had PCI with drug-elutin...
Onychomycosis is accounting for up to 50% all nail disorders. It causes not only physical but also psychosocial and emotional distress to the patient. Treatment of the disease is far from satisfactory mainly due to high cost and long duration of therapy with poor patient compliance.TAKE HOME MESSAGE:This study aims to compare the efficacy of pu...
AACE Endocrine Practice Journal: Published on May, 2022Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease affecting 25% of the global population. NAFLD is associated with cardiometabolic disorders: (1) obesity, (2) insulin resistance, (3) type 2 diabetes mellitus, (4) high blood pressure, and (5) at...
Indian Journal of Dermatology, Venereology, and Leprology: Published on 2019A 28-year-old man, undergoing treatment for vitiligo, presented with complaints of new lesions on the neck for the last 1 week. On examination, multiple hypopigmented macules were seen on the neck.Figure 1: Patient with vitiligo (red arrow) showing multiple hypopigment...
The Lancet Diabetes & Endocrinology: Published on February, 2023Metformin is increasingly being used during pregnancy, with potentially adverse long-term effects on children. This study aimed to examine adiposity in children of women with type 2 diabetes from the Metformin in Women with Type 2 Diabetes in Pregnancy (MiTy) trial, with and withou...
The Lancet: Published on January, 2023The appropriate duration of postoperative antibiotics for complex appendicitis is unclear. The increasing global threat of antimicrobial resistance warrants restrictive antibiotic use, which could also reduce side-effects, length of hospital stay, and costs.TAKE-HOME MESSAGEThis pragmatic, open-label, rando...
AHA Journal: Stroke: A Journal of Cerebral Circulation: Published on June, 2022Millions of women worldwide use exogenous hormones as oral contraceptives or hormone replacement therapy. Still, time-dependent and long-term consequences of exogenous hormones on stroke risk remains unclear.TAKE-HOME MESSAGEIn this UK Biobank analysis including 257,...
DIMS PREMIUMWhat are the DIMS Premium Features? RemoveGuidelines: 130 National & International Clinical GuidelinesManagement of Diseases: Quick Diagnosis and Management of 500 DiseasesDrug Details: 2000+ Up-to-date Drug Information with interactive featuresInvestigation Availability: Investigation’s provider names and locationsPrescription Writin...
The LANCET: Published on December, 2022Oral antivirals have been an important addition to efforts to minimise adverse COVID-19 outcomes in individuals at high risk.The earlier first trial of molnupiravir showed only a 30% reduction of hospitalisations and deaths with molnupiravir compared with placebo. Subsequent observational studies in...
JAMA Network: Published on April, 2022CVD remains a leading cause of morbidity and mortality globally. Prevention strategies must address all aspects of a patient’s lifestyle habits, including healthy nutrition, physical activity, smoking cessation, and stress reduction. When an individual’s risk is sufficiently high, pharmacologic therapy is o...
Tinea unguium (Onychomycosis) is often confused with non-infected nail dystrophy due to skin disease, particularly psoriasis (also, lichen planus). Onychomycosis may look similar to nail dystrophy due to psoriasis but those can be differentiated by presence of psoriasis in the surrounding skin with pitting nail or by circular area of...
Journal of the Women’s Health: Published on April 2021 Endometriosis is an estrogen-dependent, inflammatory condition marked anatomically by the presence of extrauterine lesions containing endometrial glands and stroma. Affecting an estimated 6%–10% of women, endometriosis is one of the most common gynecologic conditions among reproduct...