Practice-updates

JAMA: The Journal of the American Medical Association: July, 2019Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine (FT4) affects up to 10% of the adult population.Subclinical hypothyroidism may be categorized as grade 1 when...
Diabetes Care: Diabetes Journal: July, 2023Dietary sugars are associated with various health issues, including overweight, obesity, cardiovascular diseases (CVDs), and type 2 diabetes (T2D). Manufacturers have proposed alternatives to reduce added sugars, notably by substituting artificial sweeteners (e.g., aspartame, acesulfame potassium [K],...
The Journal of Sexual Medicine: January 2020Premature ejaculation (PE) is a common sexual dysfunction; the available options for PE treatment remain unsatisfactory. Premature ejaculation (PE) is the most common form of male sexual dysfunction. Globally, between 20% and 40% of men, at some point in their lives, have reported complaint of PE.The...
Principles of TherapyTopical AntifungalsTopical medications have better pharmacokinetics than their systemic counterparts. Hence, the combination is expected to have better mycological clearance than systemic and topical alone. The combination should be from different groups for wide coverage and also to prevent the emergence of resistance. Dru...
American Journal of Obstetrics & Gynecology:The levonorgestrel intrauterine system and combined oral contraceptives are the two most commonly used non-surgical treatments for heavy menstrual bleeding. However, there are limited data on their relative effectiveness and on their impact on bleeding-specific quality of life.To compare the effec...
Journal of Microbiology, Immunology and Infection: April 2023Of the four DENV serotypes (DENV-1 to DENV-4), DENV-2 and DENV-3 are frequently associated with severe secondary dengue infections.Obesity is commonly associated with numerous comorbidities and is a major health burden. According to WHO guidelines, the dengue patients who have underly...
Diabetes Research and Clinical Practice: November 21, 2022The relationship between serum uric acid levels and incident type 2 diabetes remains controversial.This cohort study assessed the association between serum uric acid levels and the incidence of type 2 diabetes in a Japanese population. TAKE-HOME MESSAGEThere was no significant associati...
The British Medical Journal (BMJ): Published June 2023About 45% of all womenTrusted Source globally use menopausal hormone therapyTrusted Source — also known as hormone replacement therapy (HRT) — to help alleviate the symptoms of menopause.The study aims to assess the association between use of menopausal hormone therapy and development of d...
Pityriasis versicolor (PV) also known as tinea versicolor, which is chronic and superficial fungal skin disease caused by Malassezia yeasts. A permanent cure may difficult to achieve and this may explain the long-term nature of the disease. Consequently, a preventive treatment regimen may help to prevent the recurrence of pityriasis versicolor....
ADA: Diabetes Journals: Published June 2023Diabetes mellitus (DM) is one of the most important causes of CKD. Moreover, both DM and CKD are important risk factors for cardiovascular disease (CVD). Metformin is still the first-line drug for DM management. The concern, of course, is an increased risk of metformin-associated lactic acidosis (MALA)...
Thyroid disease can be broadly categorised as thyroid dysfunction (hypothyroidism, hyperthyroidism) and structural disease (goitre, nodules and cancer). Management is often straightforward, but there are pitfalls that may lead to misdiagnosis, overdiagnosis and inappropriate treatment. This article reviews the approach to common thyroid proble...
Journal of the European Academy of Dermatology and Venereology: JEADV: Published: May 2023Atopic dermatitis (AD) is the most common recurrent chronic inflammation in the skin in both children and adults. It is characterized by an itchy rash with typical localization and often requires daily treatment with emollients and/or topical corticosteroi...