Practice-updates

Is Super Bioavailable Itraconazole better than Conventional Itraconazole?
Due to the changing face of dermatophytosis in India, many dermatologists practice different dosing patterns of itraconazole (ITZ). Recently, a new form of ITZ, super-bioavailable ITZ (SBITZ), has been commercialized to overcome the pharmacokinetic challenges of conventional ITZ (CITZ). ITZ is a weak base lipophilic molecule with a limite...
Artificial Intelligence in Dermatology: A Practical Introduction to a Paradigm Shift
Artificial Intelligence (AI)—the intelligence possessed by machines is having a profound impact on every aspect of the healthcare ecosystem, and dermatology is no exception.AI introduces a paradigm shift—a fundamental change—in the way we practice making it necessary for every dermatologist to have a broad understanding of AI. RemoveAvailable N...
A Point-of-Care, Real-Time Artificial Intelligence System to Support Clinician Diagnosis of a Wide Range of Skin Diseases
Journal of Investigative Dermatology: May 2021The presentation of skin disease varies widely across skin types, disease acuity, immune status, and treatment history. Thus, dermatological diagnosis remains challenging.The broad range of possible skin diseases and presentations of those diseases makes this challenge particularly well suited for a...
Benefits and Safety of Platelet-Rich Plasma Injection for Treating Patients with Dry Eye Disease
Contact Lens & Anterior Eye: Published November 2023Dry eye disease has public health and economic significance. Platelet-rich plasma is rich in anti-inflammatory agents and growth factors, both beneficial for ocular surface repair. This study aimed to conduct a systematic review and meta-analysis to summarize the benefits of platelet-rich plas...
Hydroxychloroquine Is Safe and Effective for the Management of Oral Lichen Planus
Oral Diseases Journal: September. 2023This study was aimed to evaluate the safety and benefit of short-term application of hydroxychloroquine in the management of atrophic/erosive/ulcerative oral lichen planus (OLP).TAKE-HOME MESSAGEIn this study, after 4 weeks of treatment, the systemic use of hydroxychloroquine and the topical use of dexameth...
Outcomes of Using Cefepime vs Piperacillin–Tazobactam in Adults Hospitalized with Acute Infection
JAMA: The Journal of the American Medical Association: October, 2023Cefepime and piperacillin-tazobactam are commonly administered to hospitalized adults for empirical treatment of infection. Although piperacillin-tazobactam has been hypothesized to cause acute kidney injury and cefepime has been hypothesized to cause neurological dysfunction,...
Effectiveness of Luliconazole for the Treatment of Tinea Infections
The prevalence of superficial fungal infections across the globe is increasing from 20-25%. Superficial infections are mostly caused by dermatophytes. Depending on the site affected, the dermatophytes are clinically classified as Tinea capitis (head), Tinea faciei (face), Tinea barbae (beard), Tinea manus (hand), Tinea corporis (body), Tinea c...
Association of Proton Pump Inhibitor Use with the Risk of Kidney Stones
BMJ Open: Published, October, 2023This study aimed to investigate the potential association between PPI use and kidney stones by analysing National Health and Nutrition Examination Survey (NHANES) data from 2007 to 2018. TAKE-HOME MESSAGEThe authors of this large US-based cross-sectional study found that proton-pump inhibitor (PPI) use was asso...
Oral Medications to Treat Toenail Fungal Infection
JAMA: The Journal of the American Medical AssociationThe authors investigated different oral antifungal medications used to treat toenail fungal infections.TAKE-HOME MESSAGECompared with placebo, high-quality evidence supports better clinical (ie, normal appearance of the toenail) and mycological (negative culture, microscopy, or both) results...
The unprecedented epidemic-like scenario of Dermatophytosis: Antifungal resistance and treatment options
There has been a significant increase in the incidence of chronic, relapsing, recurrent cases of superficial dermatophytosis in India that are also often unresponsive to conventional drugs and doses of recommended antifungal treatment. Almost 15– 20% of the outpatient department cases are those of chronic dermatophytosis. Recurrences and relaps...
DENGUE outbreak: what are the VACCINE options?
Dengue fever has been a significant public health issue in Bangladesh over the years. Our country has experienced periodic outbreaks of dengue, particularly during the monsoon season when the mosquito population increases. The dengue outbreak in Bangladesh has taken a worrisome turn as the number of cases and fatalities continues to rise, sign...
Association of Thyroid Disorders in reproductive age presenting with abnormal uterine bleeding
International Journal of Clinical Obstetrics and Gynecology: Published 2021Abnormal uterine bleeding is defined as any type of bleeding that is abnormal in volume, frequency, duration and periodicity. Frequent complaints include heavy and prolonged menstrual bleeding with or without pain, passage of clots, fatigue and lethargy. AUB is...