Endocrine-disorders

PubMed Central: IntroductionThreatened miscarriage is a common disease during early pregnancy, with a morbidity of 30% to 40%, which could develop into a complete miscarriage or dystocia without timely treatment. Many pathogenic factors contribute to the threatened miscarriage, of which lacking progestogens due to the endocrine dysfunction of...
Key Information: Progesterone is essential for the maintenance of a healthy pregnancy. Progesterone is frequently prescribed to patients presenting with per vaginal (PV) bleeding in early pregnancy and a history of recurrent pregnancy loss. Any defect in the secretion of human chorionic gonadotropin or progesterone is associated with...
ADA Diabetes Care Journal: Metformin is the recommended first-line pharmacotherapy for patients with type 2 diabetes, but most patients will ultimately require additional therapies to maintain glycemic control. Maintaining intensive glucose control early in the disease process may lead to legacy benefits that persist beyond the per...
The Journal of Laryngology & OtologyThyroidectomy is one of the most common interventions in general and endocrine surgery for patients with hyperthyroidism, goiter, thyroid nodules or thyroid cancer.Post-operative hypocalcaemia is a recognized complication of thyroid surgery. The most common cause of acute symptomatic hypocalcemia in hospitali...
BMJ Open Diabetes Research & Care: BMJ Journal Bangladeshi researchers identify new pathological cause of diabetes. The team of researchers from multiple local and foreign universities, through a five-year (2015-2020) study on 574 non-diabetic people aged between 30 and 60, have discovered that deficiency of the Intestinal Alkaline Ph...
Diabetes Journal: ADA publications Several randomized clinical trials have shown the possibility of preventing or delaying the onset of type 2 diabetes in nondiabetic adults at high risk of developing the disease. Successful interventions have included drugs (not further discussed here) and lifestyle interventions emphasizing weight loss...
In patients with type 2 diabetes mellitus, insulin may be used to augment therapy with oral glycemic medications or as insulin replacement therapy.The goals of therapy should be individualized based on many factors, including age, life expectancy, comorbid conditions, duration of diabetes, risk of hypoglycemia, cost, patient motivation, and qu...
Hormone therapy is the most effective treatment for vasomotor symptoms (VMS) and other menopausal symptoms. Changing estrogen levels during menopause may impact multiple components involved in maintaining temperature homeostasis.Health care professionals should individualize therapy based on clinical factors and patient preference. They should...
The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Recommendations Chronic Kidney Disease - Screening At...
Studies clarify menopausal HT’s impact on breast cancer riskOne of the greatest concerns of women who are considering Menopausal Hormone Therapy (MHT) is the relationship between hormone use and breast cancer. Data from the The Women’s Health Initiative (WHI) suggest an increase in risk with combined estrogen-progestin therapy, but a reduction i...
JAMA Internal MedicineTAKE-HOME MESSAGEThis retrospective study evaluated the association between statin initiation and diabetes progression. Progression of diabetes occurred in significantly more statin users. There was a dose–response relationship with higher-intensity statin use.The study examined 12 years of data on patients covered by the...
Treatment guidelines for type 2 diabetes mellitus (T2DM) recommend initiating pharmacotherapy with an oral antidiabetic drug (OAD) to reduce hyperglycaemia when diet and exercise are inadequate. International guidelines recommend metformin as the first OAD, whereas Japanese guidelines recognize that other OADs may be more appropriate i...