Cardiovascular-disorders

The LANCET: Diabetes & Endocrinology: Published on July, 2022Diabetes is a major cause of death, cardiovascular complications, and health-care burden worldwide.People with type 2 diabetes who have high blood pressure are at an increased risk of morbidity and death from major cardiovascular events.However, there are inadequate randomised contro...
The New England Journal of Medicine (NEJM): Published on April, 2022Antihypertensive treatment during pregnancy reduces the frequency of severe hypertension (blood pressure, ≥160/110 mm Hg) but has not been shown to improve maternal, fetal, or neonatal outcomes and has been associated with an increased risk of small-for-gestational-age birth w...
The 2021 WHO hypertension guideline aims to provide the most current and relevant evidence based global public health guidance on the initiation of treatment (with pharmacological agents) for hypertension in adults. The recommendations target adult, non-pregnant patients who were appropriately diagnosed with hypertension and counseled about li...
AHA Journals: Hypertension: Published on May, 2022Diabetes is a strong risk factor for end-stage renal disease (ESRD). Hypertension also plays a crucial role in the development and progression of kidney failure. Blood pressure (BP) rises with declining kidney function which in turn aggravates hypertension. Moreover, as chronic kidney disease (C...
ACP Journals: Annals of Internal Medicine: Published on November, 2022Current guidelines recommend using direct oral anticoagulants (DOACs) over warfarin in patients with atrial fibrillation (AF), but head-to-head trial data do not exist to guide the choice of DOAC.The aim of the study is to do a large-scale comparison between all DOACs (apix...
The Lancet: Published on October, 2022Hypertension, or high blood pressure, is a key risk factor for cardiovascular disease worldwide. Previous clinical trials supporting the cardiovascular benefits of antihypertensive therapy primarily use conventional morning dosing. Additionally, cardiovascular events are temporally associated with the morni...
European Heart Journal: September, 2022Cardiovascular (CV) disease (CVD) is the leading cause of morbidity and mortality worldwide, despite continuous improvement of medical treatment, diagnosis, and risk factor control. It has been clearly demonstrated that statin therapy confers significant mortality and morbidity benefits in both the primary...
Journal of the American Heart Association (AHA): Published on November, 2022Sleep, alongside diet and physical activity (PA), is one of the 3 pillars of health, but unlike other health behaviors, healthy sleep is not included in the American College of Cardiology/American Heart Association (AHA) cardiovascular disease (CVD) prevention guideline...
Journal of the American College of Cardiology: Published on December, 2022Healthy dietary patterns are rich in micronutrients, but their influence on cardiovascular disease (CVD) risks has not been systematically quantified.The goal of this study was to provide a comprehensive and most up-to-date evidence-based map that systematically quantifi...
AHA Journal: Circulation: Published on February, 2023Low-density lipoprotein cholesterol (LDL-C) level is a well-established risk factor for atherosclerotic cardiovascular disease. However, the optimal achieved LDL-C level with regard to efficacy and safety in the long term remains unknown.TAKE-HOME MESSAGEThis study assessed the relationship...
The Lancet: The traditional Mediterranean diet consisted of a high proportion of fruits, vegetables, nuts, legumes, and cereals, a moderate intake of fish and poultry as the main protein source and olive oil as the main fat source. A low intake of dairy products, red meat, processed meats, and sweets. Current recommendation for patient...
JAMA Cardiology: Published on June, 2022 TAKE-HOME MESSAGE Question: Is starting cardiac rehabilitation exercise training 2 weeks after sternotomy as effective and safe as starting 6 weeks after sternotomy? Findings: In this assessor-blind, noninferiority, randomized clinical trial of 158 cardiac surgery patients, starting cardiac...